Cereblon Targeting Ligands Plus Linkers

Products
文献 (2)

Building Blocks

Cat. No. 产品名称/活性
7516 Lenalidomide 4'-alkylC3-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7517 Lenalidomide 4'-alkylC5-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7075 Lenalidomide 4'-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7513 Lenalidomide 4'-PEG1-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7093 Lenalidomide 4'-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7514 Lenalidomide 4'-PEG2-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7076 Lenalidomide 4'-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7677 Lenalidomide 5'-amine
Cereblon ligand with terminal amine for onward chemistry
7472 Lenalidomide 5'-piperazine
Cereblon ligand with terminal piperazine for onward chemistry
7473 Lenalidomide 5'-piperazine-4-methylpiperidine
Cereblon ligand with terminal piperidine for onward chemistry
7994 PAG 3'-fluoro-4'-piperazine
Functionalized cereblon ligand for PROTAC development
7996 PAG 3'-piperazine
Functionalized cereblon ligand for PROTAC development
7997 PAG 3'-piperazine-4-methylpiperidine
Cereblon ligand with terminal piperidine for onward chemistry
7998 PAG 4'-piperazine
Functionalized cereblon ligand for PROTAC development
7999 PAG 4'-piperazine-4-methylpiperidine
Cereblon ligand with terminal piperidine for onward chemistry
7732 Pomalidomide 4'-alkylC10-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6851 Pomalidomide 4'-alkylC2-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7439 Pomalidomide 4'-alkylC2-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7096 Pomalidomide 4'-alkylC3-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7205 Pomalidomide 4'-alkylC3-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7440 Pomalidomide 4'-alkylC3-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7209 Pomalidomide 4'-alkylC4-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7441 Pomalidomide 4'-alkylC4-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
6682 Pomalidomide 4'-alkylC5-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6716 Pomalidomide 4'-alkylC5-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7442 Pomalidomide 4'-alkylC5-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7210 Pomalidomide 4'-alkylC6-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7923 Pomalidomide 4'-alkylC6-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7443 Pomalidomide 4'-alkylC6-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7097 Pomalidomide 4'-alkylC7-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7208 Pomalidomide 4'-alkylC7-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7211 Pomalidomide 4'-alkylC8-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6944 Pomalidomide 4'-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7094 Pomalidomide 4'-PEG1-acid
Cereblon ligand with PEG linker and terminal acid for onward chemistry
7203 Pomalidomide 4'-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7434 Pomalidomide 4'-PEG1-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7212 Pomalidomide 4'-PEG2-acid
Cereblon ligand with PEG linker and terminal acid for onward chemistry
6637 Pomalidomide 4'-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7307 Pomalidomide 4'-PEG2-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
6681 Pomalidomide 4'-PEG3-acid
Cereblon ligand with PEG linker and terminal acid for onward chemistry
7204 Pomalidomide 4'-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7435 Pomalidomide 4'-PEG3-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7213 Pomalidomide 4'-PEG4-acid
Cereblon ligand with PEG linker and terminal acid for onward chemistry
6963 Pomalidomide 4'-PEG4-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7436 Pomalidomide 4'-PEG4-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7095 Pomalidomide 4'-PEG5-acid
Cereblon ligand with PEG linker and terminal acid for onward chemistry
7924 Pomalidomide 4'-PEG5-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7437 Pomalidomide 4'-PEG5-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
7470 Pomalidomide 5'-fluoro-6'-piperazine
Cereblon ligand with terminal piperazine for onward chemistry
7471 Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine
Cereblon ligand with terminal piperidine for onward chemistry
7468 Pomalidomide 5'-piperazine
Cereblon ligand with terminal piperazine for onward chemistry
7469 Pomalidomide 5'-piperazine-4-methylpiperidine
Cereblon ligand with terminal piperidine for onward chemistry
7913 Pomalidomide 5'-piperidine-acid
Cereblon ligand with piperidine linker and terminal acid for onward chemistry
7329 Thalidomide 4'-ether-alkylC2-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6850 Thalidomide 4'-ether-alkylC2-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7330 Thalidomide 4'-ether-alkylC3-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7521 Thalidomide 4'-ether-alkylC3-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7331 Thalidomide 4'-ether-alkylC4-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6917 Thalidomide 4'-ether-alkylC4-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7332 Thalidomide 4'-ether-alkylC5-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7522 Thalidomide 4'-ether-alkylC5-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7333 Thalidomide 4'-ether-alkylC6-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
6627 Thalidomide 4'-ether-alkylC6-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7829 Thalidomide 4'-ether-alkylC6-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
7334 Thalidomide 4'-ether-alkylC7-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7335 Thalidomide 4'-ether-alkylC8-acid
Cereblon ligand with alkyl linker and terminal acid for onward chemistry
7403 Thalidomide 4'-ether-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7518 Thalidomide 4'-ether-PEG1-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
6686 Thalidomide 4'-ether-PEG2-alkyne
Cereblon ligand with PEG linker and terminal alkyne for onward chemistry
7519 Thalidomide 4'-ether-PEG2-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
6950 Thalidomide 4'-ether-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7520 Thalidomide 4'-ether-PEG3-azide
Cereblon ligand with PEG linker and terminal azide for onward chemistry
6951 Thalidomide 4'-ether-PEG5-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6913 Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine
Cereblon ligand with alkyl-PEG-alkyl linker and terminal amine for onward chemistry
6949 Thalidomide 4'-oxyacetamide-alkylC2-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6300 Thalidomide 4'-oxyacetamide-alkylC4-azide
Cereblon ligand with alkyl linker and terminal azide for onward chemistry
6968 Thalidomide 4'-oxyacetamide-alkylC6-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6946 Thalidomide 4'-oxyacetamide-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
6966 Thalidomide 4'-oxyacetamide-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6967 Thalidomide 4'-oxyacetamide-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
6467 Thalidomide 4'-oxyacetamide-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7733 Thalidomide 5'-amine-alkylC10-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7988 Thalidomide 5'-amine-alkylC6-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7557 Thalidomide 5'-amine-alkylC8-amine
Cereblon ligand with alkyl linker and terminal amine for onward chemistry
7735 Thalidomide 5'-amine-PEG1-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7736 Thalidomide 5'-amine-PEG2-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry
7737 Thalidomide 5'-amine-PEG3-amine
Cereblon ligand with PEG linker and terminal amine for onward chemistry

Literature for Cereblon Targeting Ligands Plus Linkers

Tocris offers the following scientific literature for Cereblon Targeting Ligands Plus Linkers to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


TPD and Induced Proximity Research Product Guide

TPD and Induced Proximity Research Product Guide

This brochure highlights the tools and services available from Bio-Techne to support your Targeted Protein Degradation and Induced Proximity research, including:

  • Active Degraders
  • TAG Degradation Platform
  • Degrader Building Blocks
  • Assays for Protein Degradation
  • Induced Proximity Tools
Targeted Protein Degradation Poster

Targeted Protein Degradation Poster

Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia