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Submit ReviewLUF 6283
Discontinued Product
4881 has been discontinued.
View all Hydroxycarboxylic Acid Receptors products.
说明： HCA2 (GPR109A) partial agonist
化学名： 5-Butyl-1H-pyrazole-3-carboxylic acid
纯度： ≥98% (HPLC)
生物活性 for LUF 6283
LUF 6283 is a partial agonist of hydroxycarboxylic acid receptor 2 (HCA2) (Ki = 0.55 μM). Thought to lower plasma very-low-density lipoprotein (VLDL)-triglyceride levels by affecting hepatic VLDL production in normolipidemic C57BL/6 mice.
技术数据 for LUF 6283
| 分子量 | 168.19 |
| 公式 | C8H12N2O2 |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 92933-48-7 |
| PubChem ID | 6485181 |
| InChI Key | ZJTXSGLJNBAMJS-UHFFFAOYSA-N |
| Smiles | CCCCC1=CC(C(O)=O)=NN1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for LUF 6283
参考文献 for LUF 6283
参考文献是支持产品生物活性的出版物。
Li et al (2012) Effects of pyrazole partial agonists on HCA2-mediated flushing and VLDL-triglyceride levels in mice. Br.J.Pharmacol. 167 818 PMID: 22616721
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关键词: LUF 6283, LUF 6283 supplier, LUF6283, HCA2, hydroxycarboxylic, acid, receptors, GPR109A, HM74A, partial, agonists, Hydroxycarboxylic, Acid, Receptors, 4881, Tocris Bioscience
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