LY 310762 hydrochloride

Cat. No. 3078 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Selective 5-HT_1D antagonist

化学名： 1-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-one hydrochloride

纯度： ≥98% (HPLC)

引用文献 (1)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for LY 310762 hydrochloride

LY 310762 hydrochloride is a 5-HT_1D-preferring receptor antagonist (EC₅₀= 31 nM). Displays no activity on 5-HT transport.

许可信息

Sold under license from Eli Lilly and company

化合物库 for LY 310762 hydrochloride

LY 310762 hydrochloride is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for LY 310762 hydrochloride

分子量	430.94
公式	C₂₄H₂₇FN₂O₂.HCl
储存	Desiccate at RT
纯度	≥98% (HPLC)
CAS Number	192927-92-7
PubChem ID	11957576
InChI Key	BOCLFQZPFYNVFD-UHFFFAOYSA-N
Smiles	CC(C1=CC=CC=C1N2CCN3CCC(C(C4=CC=C(F)C=C4)=O)CC3)(C)C2=O.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for LY 310762 hydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	water	4.31	10
	DMSO	43.09	100

制备储备液 for LY 310762 hydrochloride

以下数据基于产品分子量 430.94。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	2.32 mL	11.6 mL	23.21 mL
5 mM	0.46 mL	2.32 mL	4.64 mL
10 mM	0.23 mL	1.16 mL	2.32 mL
50 mM	0.05 mL	0.23 mL	0.46 mL

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产品说明书 for LY 310762 hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for LY 310762 hydrochloride

参考文献是支持产品生物活性的出版物。

Pullar et al (2004) The role of the 5-HT_1D receptor as a presynaptic autoreceptor in the guinea pig. Eur.J.Pharmacol. 493 85 PMID: 15189767

If you know of a relevant reference for LY 310762 hydrochloride, please let us know.

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关键词: LY 310762 hydrochloride, LY 310762 hydrochloride supplier, 5-HT1D-preferring, antagonists, Serotonin, Receptors, LY310762, hydrochloride, 5-HT1D, 3078, Tocris Bioscience

1 篇 LY 310762 hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 LY 310762 hydrochloride 的部分引用包括：

Conley et al (2015) Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti. Pain 352 53 PMID: 25332454

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