m-3M3FBS

Cat. No. 1941 7 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Phospholipase C activator

化学名： 2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide

纯度： ≥98% (HPLC)

引用文献 (7)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for m-3M3FBS

m-3M3FBS is an activator of phospholipase C (PLC). Stimulates superoxide generation, Ca²⁺ release and inositol phosphate formation in a variety of cell types. Also inhibits growth of the leukemic cell lines U937 and THP-1.

Negative Control also available.

化合物库 for m-3M3FBS

m-3M3FBS is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for m-3M3FBS

分子量	343.36
公式	C₁₆H₁₆F₃NO₂S
储存	Store at RT
纯度	≥98% (HPLC)
CAS Number	200933-14-8
PubChem ID	761523
InChI Key	ZIIUUSVHCHPIQD-UHFFFAOYSA-N
Smiles	CC1=CC(C)=C(C(C)=C1)S(=O)(=O)NC1=CC=CC(=C1)C(F)(F)F

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for m-3M3FBS

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	ethanol	34.34	100
	DMSO	34.34	100

制备储备液 for m-3M3FBS

以下数据基于产品分子量 343.36。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	2.91 mL	14.56 mL	29.12 mL
5 mM	0.58 mL	2.91 mL	5.82 mL
10 mM	0.29 mL	1.46 mL	2.91 mL
50 mM	0.06 mL	0.29 mL	0.58 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

Dilution Calculator

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产品说明书 for m-3M3FBS

分析证书/产品说明书

化学品安全技术说明书

参考文献 for m-3M3FBS

参考文献是支持产品生物活性的出版物。

Bae et al (2003) Identification of a compound that directly stimulates phospholipase C activity. Mol.Pharmacol. 63 1043 PMID: 12695532

Krjukova et al (2004) Phospholipase C activator m-3M3FBS affects Ca²⁺ homeostasis independently of phospholipase C activation. Br.J.Pharmacol. 143 3 PMID: 15302681

Lee et al (2005) The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis. Cancer Lett. 222 227 PMID: 15863272

If you know of a relevant reference for m-3M3FBS, please let us know.

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关键词: m-3M3FBS, m-3M3FBS supplier, Phospholipases, C, activators, activates, PLC, esterases, Phospholipase, Enzyme, Substrates, /, Activators, 1941, Tocris Bioscience