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Submit ReviewMag-Fura-2 AM
说明： Magnesium (Mg2+) indicator, membrane permeable
化学名： Bis(acetoxymethyl) 2,2'-((5-(2-(acetoxymethoxy)-2-oxoethoxy)-2-(5-((acetoxymethoxy)carbonyl)oxazol-2-yl)benzofuran-6-yl)azanediyl)diacetate
纯度： ≥95% (HPLC)
生物活性 for Mag-Fura-2 AM
Mag-Fura-2 AM is a cell-permeable fluorescent magnesium ion (Mg2+) indicator. It shows selectivity for Mg2+ over other bivalent ions (Zn2+, Cu2+ and Ca2+). It exhibits >13,000-fold selectivity for Mg2+ ions over Ca2+ ions (Mg2+ Kd = 1.9 nM vs Ca2+ Kd = 25 μM). Excitation and emission maxima (λ) are 369 and 511 nm, respectively. Mag-Fura-2 AM can be used as an indirect indicator of ATP consumption/production.
It is recommended to prepare stock solutions in DMSO.
Optical Data for Mag-Fura-2 AM
| λabs | 369 nm |
|---|---|
| λem | 511 nm |
| Extinction Coefficient (ε) | 31000 M-1cm-1 |
| Cell Permeable | Yes |
| Application | Confocal Imaging, Flow Cytometry |
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
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技术数据 for Mag-Fura-2 AM
| 分子量 | 722.57 |
| 公式 | C30H30N2O19 |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 130100-20-8 |
| PubChem ID | 131176 |
| InChI Key | PCDUVTXECKTHBH-UHFFFAOYSA-N |
| Smiles | O=C(C1=CN=C(C2=CC3=C(C=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OCC(OCOC(C)=O)=O)=C3)O2)O1)OCOC(C)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Mag-Fura-2 AM
参考文献 for Mag-Fura-2 AM
参考文献是支持产品生物活性的出版物。
Schütz et al (2021) Trophectoderm cell failure leads to peri-implantation lethality in Trpm7-deficient mouse embryos. Cell Rep. 37 109851 PMID: 34686339
Watanabe et al (2022) Chronic magnesium deficiency causes reversible mitochondrial permeability transition pore opening and impairs hypoxia tolerance in the rat heart. J.Pharmacol.Sci. 148 238 PMID: 35063139
Cheng et al (2021) Variability of mitochondrial energy balance across brain regions. J.Neurochem. 157 1234 PMID: 33190229
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Fluorescent Dyes and Probes Research Product Guide
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