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MD15

Cat. No. 7504 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Negative control for MD13 (Cat. No. 7503)
化学名： N-(4-(7-Hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)-8-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octanamide
纯度： ≥98% (HPLC)
说明书
引用文献
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文献 (2)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for MD15

MD15 is a negative control for MD13 (Cat. No. 7503).

许可信息

Sold with kind permission of Professor Dekker.

技术数据 for MD15

分子量 667.72
公式 C36H37N5O8
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 2758431-98-8
InChI Key KJFPENGEMHTUFD-UHFFFAOYSA-N
Smiles O=C1N(C2=CC=C(NC(CCCCCCCNC3=C(C(N(C4CCC(N(C4=O)C)=O)C5=O)=O)C5=CC=C3)=O)C=C2)CC6=CC=C(O)C=C6O1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for MD15

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 66.77 100

制备储备液 for MD15

以下数据基于产品分子量 667.72。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 1.5 mL 7.49 mL 14.98 mL
5 mM 0.3 mL 1.5 mL 3 mL
10 mM 0.15 mL 0.75 mL 1.5 mL
50 mM 0.03 mL 0.15 mL 0.3 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Dilution Calculator

Calculate the dilution required to prepare a stock solution.
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参考文献 for MD15

参考文献是支持产品生物活性的出版物。

If you know of a relevant reference for MD15, please let us know.

按标靶查看相关产品

关键词: MD15, MD15 supplier, negative, control, degraders, macrophage, migration, inhibitory, factor, MIF, PROTAC, Cytokines, Negative, Controls, 7504, Tocris Bioscience

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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

TPD and Induced Proximity Research Product Guide

TPD and Induced Proximity Research Product Guide

This brochure highlights the tools and services available from Bio-Techne to support your Targeted Protein Degradation and Induced Proximity research, including:

  • Active Degraders
  • TAG Degradation Platform
  • Degrader Building Blocks
  • Assays for Protein Degradation
  • Induced Proximity Tools
Targeted Protein Degradation Poster

Targeted Protein Degradation Poster

Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia