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Submit ReviewMethylnaltrexone bromide
Discontinued Product
6109 has been discontinued.
说明： μ antagonist; peripherally restricted
化学名： 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium bromide
纯度： ≥98% (HPLC)
生物活性 for Methylnaltrexone bromide
Methylnaltrexone bromide is a peripherally restricted μ-opioid antagonist. Antagonizes the effects of morphine (Cat. No. 5158) on contraction of isolated guinea pig ileum. Quaternary derivative of naltrexone (Cat. No. 0677).
技术数据 for Methylnaltrexone bromide
| 分子量 | 436.34 |
| 公式 | C21H26BrNO4 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 73232-52-7 |
| PubChem ID | 5361917 |
| InChI Key | IFGIYSGOEZJNBE-KNLJMPJLSA-N |
| Smiles | O=C1[C@H]2C34C5=C(O2)C(O)=CC=C5CC([N+](CC6CC6)(C)CC4)[C@]3(O)CC1.[Br-] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Methylnaltrexone bromide
参考文献 for Methylnaltrexone bromide
参考文献是支持产品生物活性的出版物。
Valentino et al (1981) Quaternary naltrexone: evidence for the central mediation of discriminative stimulus effects of narcotic agonists and antagonists. J.Pharmacol.Exp.Ther. 217 652 PMID: 6262493
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关键词: Methylnaltrexone bromide, Methylnaltrexone bromide supplier, peripheral, opioid, antagonists, antagonism, mu, receptor, Mu, Opioid, Receptors, 6109, Tocris Bioscience
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