Moexipril hydrochloride

Name: Moexipril hydrochloride
Brand: Tocris Bioscience
SKU: 2691

Cat. No. 2691 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2691 has been discontinued.

View all Angiotensin-Converting Enzyme products.

说明： Angiotensin-converting enzyme (ACE) inhibitor

别名： RS 10085

化学名： 2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid hydrochloride

纯度： ≥99% (HPLC)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Moexipril hydrochloride

Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC₅₀ values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.

技术数据 for Moexipril hydrochloride

分子量	535.03
公式	C₂₇H₃₄N₂O₇.HCl
储存	Desiccate at +4°C
纯度	≥99% (HPLC)
CAS Number	82586-52-5
PubChem ID	54889
InChI Key	JXRAXHBVZQZSIC-JKVLGAQCSA-N
Smiles	O=C([C@@H](N[C@H]([C@@](OCC)=O)CCC3=CC=CC=C3)C)N2CC1=CC(OC)=C(OC)C=C1C[C@H]2[C@@](O)=O.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Moexipril hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Moexipril hydrochloride

参考文献是支持产品生物活性的出版物。

Edling et al (1995) Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enal. J.Pharmacol.Exp.Ther. 275 854 PMID: 7473177

Chrysant and Chrysant (2004) Pharmacological and clinical profile of moexipril: a concise review. J.Clin.Pharmacol. 44 827 PMID: 15286086

Friehe and Ney (1997) Pharmacological and toxicological studies of the new angiotensin converting enzyme inhibitor moex. hydrochloride. Arzneim.-Forsch. 47 132

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