Neuromedin N (rat, mouse, porcine, canine)

Name: Neuromedin N (rat, mouse, porcine, canine)
Brand: Tocris Bioscience
SKU: 1907

Cat. No. 1907 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1907 has been discontinued.

View all Neurotensin Receptors products.

说明： Neurotensin-like peptide

说明书

引用文献

文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Neuromedin N (rat, mouse, porcine, canine)

Neuromedin N (rat, mouse, porcine, canine) is an endogenous neurotensin-like neuropeptide, originally isolated from porcine spinal cord. Binds to neurotensin receptors (IC₅₀ = 16.7 nM for inhibition of [Trp¹¹]-NT binding to rat brain receptors). Regulates guinea pig intestinal smooth muscle contraction and produces hypotension in rats. Also induces hypothermia following central administration in rats in vivo.

技术数据 for Neuromedin N (rat, mouse, porcine, canine)

分子量	745.96
公式	C₃₈H₆₃N₇O₈
序列	KIPYIL
储存	Desiccate at -20°C
CAS Number	92169-45-4
PubChem ID	9940301
InChI Key	RZMLVIHXZGQADB-YLUGYNJDSA-N
Smiles	[H]N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Neuromedin N (rat, mouse, porcine, canine)

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Neuromedin N (rat, mouse, porcine, canine)

参考文献是支持产品生物活性的出版物。

Checler et al (1986) Neuromedin N: high affinity interaction with neurotensin receptors and rapid inactivation by brain synaptic peptidases. Eur.J.Pharmacol. 126 239 PMID: 3019713

Dubuc et al (1988) Hypothermic effect of neuromedin N in mice and its potentiation by peptidase inhibitors. Eur.J.Pharmacol. 151 117 PMID: 3416919

Minamino et al (1984) Neuromedin N: a novel neurotensin-like peptide identified in porcine spinal cord. Biochem.Biophys.Res.Commun. 122 542 PMID: 6547840

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关键词: Neuromedin N, Neuromedin N supplier, Neurotensin-like, peptide, NT, Receptors, Neurotensin, agonists, NeuromedinN, 1907, Tocris Bioscience

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