Neuromedin S (rat)

Name: Neuromedin S (rat)
Brand: Tocris Bioscience
SKU: 3648

Cat. No. 3648 1 次引用提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3648 has been discontinued.

View all Neuromedin U Receptors products.

说明： Potent, endogenous NMU₁ and NMU₂ agonist

说明书

引用文献 (1)

生物活性技术数据说明书参考文献

生物活性 for Neuromedin S (rat)

Neuromedin S (rat) is a potent, endogenous neuromedin U receptor agonist (EC₅₀ values are 65 and 91 pM at NMU₁ and NMU₂ respectively). Induces phase shifts in the circadian rhythm of locomotor activity following i.c.v. administration. Potent endogenous anorexigenic peptide.

技术数据 for Neuromedin S (rat)

分子量	4241.97
公式	C₁₉₃H₃₀₇N₅₇O₄₉S
序列	LPRLLHTDSRMATIDFPKKDPTTSLGRPFFLFRPRN (Modifications: Asn-36 = C-terminal amide)
储存	Store at -20°C
CAS Number	843782-19-4
PubChem ID	90488896
InChI Key	FJADBVUPVZKUEP-OFGSCBOVSA-N
Smiles	[H]N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Neuromedin S (rat)

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Neuromedin S (rat)

参考文献是支持产品生物活性的出版物。

Mori et al (2005) Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J. 24 325 PMID: 15635449

Ida et al (2005) Neuromedin S is a novel anorexigenic hormone. Endocrinology 146 4217 PMID: 15976061

Mitchell et al (2009) Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S. Br.J.Pharmacol. 158 87 PMID: 19519756

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关键词: Neuromedin S (rat), Neuromedin S (rat) supplier, Potent, endogenous, NMU1, and, NMU2, agonists, Neuromedin, U, Receptors, NeuromedinS, (rat), circadian, rhythms, 3648, Tocris Bioscience

1 篇 Neuromedin S (rat) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Neuromedin S (rat) 的部分引用包括：

Sampson et al (2018) Small-Molecule Neuromedin U Receptor 2 Agonists Suppress Food Intake and Decrease Visceral Fat in Animal Models. Pharmacol Res Perspect 6 e00425 PMID: 30151213

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