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Neuromedin U (rat)

Cat. No. 1917 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1917 has been discontinued.

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说明： Endogenous modulator of blood pressure and flow, gut ion transport, feeding and body temperature
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for Neuromedin U (rat)

Endogenous peptide regulating blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function. Also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo.

技术数据 for Neuromedin U (rat)

分子量 2643
公式 C124H180N34O31
序列 YKVNEYQGPVAPSGGFFLFRPRN

(Modifications: Asn-23 = C-terminal amide)
储存 Desiccate at -20°C
CAS Number 117505-80-3
PubChem ID 71311710
InChI Key YYDRKWCPVLDJJD-XOXVDEAXSA-N
Smiles [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Neuromedin U (rat)

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化学品安全技术说明书

参考文献 for Neuromedin U (rat)

参考文献是支持产品生物活性的出版物。

Minamino et al (1985) Neuromedin U-8 and U-25: novel uterus stimulating and hypertensive peptides identified in porcine spinal cord. Biochem.Biophys.Res.Commun. 130 1078 PMID: 3841690

Mondal et al (2003) Neuromedin U acts in the cental nervous system to inhibit gastric acid secretion via CRH system. Am.J.Physiol.Gastrointest.Liver Physiol. 284 G963 PMID: 12584108

Szekeres et al (2000) Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. J.Biol.Chem. 275 20247 PMID: 10811630

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关键词: Neuromedin U (rat), Neuromedin U (rat) supplier, NMU, Receptors, agonists, NeuromedinU, (rat), Neuromedin, U, 1917, Tocris Bioscience

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