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Submit ReviewEndogenous antiopioid peptide, implicated in pain modulation and endocrine functions. Potently activates the orphan G-protein-coupled receptor HLWAR77 (NPFF2) (EC50 = 0.39 nM).
分子量 | 1367.57 |
公式 | C65H94N18O15 |
序列 |
SQAFLFQPQRF (Modifications: Phe-11 = C-terminal amide) |
储存 | Desiccate at -20°C |
CAS Number | 192387-39-6 |
Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Elshourbagy et al (2000) Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor. J.Biol.Chem. 275 25965 PMID: 10851242
关键词: Neuropeptide SF (human), Neuropeptide SF (human) supplier, Implicated, pain, modulation, Anti-opioids, NPFF, Receptors, Neuropeptides, FF/AF, HLWAR77, NPFFR2, NeuropeptideSF, (human), npff2, neuropeptide, Neuropeptide, (human, FMRFamide-related), Miscellaneous/Non-selective, Opioids, 1886, Tocris Bioscience
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