Neuropeptide SF (mouse, rat)

Name: Neuropeptide SF (mouse, rat)
Brand: Tocris Bioscience
SKU: 3647

Cat. No. 3647 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

3647 has been discontinued.

View all Neuropeptide FF/AF Receptors products.

说明： NPFF1 and NPFF2 agonist

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for Neuropeptide SF (mouse, rat)

Neuropeptide SF (mouse, rat) is a neuropeptide FF receptor agonist (K_i values are 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). Potentiates the antinociceptive action of morphine in vivo and reverses the loss of morphine potency in tolerant animals. Also increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3) (EC₅₀ ~ 50 μM).

技术数据 for Neuropeptide SF (mouse, rat)

分子量	888.03
公式	C₄₀H₆₅N₁₃O₁₀
序列	SLAAPQRF (Modifications: Phe-8 = C-terminal amide)
储存	Store at -20°C
CAS Number	230960-31-3
PubChem ID	90488868
InChI Key	OLOSAWFREOVGQW-CJKZIAQFSA-N
Smiles	[H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Neuropeptide SF (mouse, rat)

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Neuropeptide SF (mouse, rat)

参考文献是支持产品生物活性的出版物。

Deval et al (2003) Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability. Neuropharmacology 44 662 PMID: 12668052

Jhamandas et al (2006) Facilitation of spinal mor. analgesia in normal and mor. tolerant animals by neuropeptide SF and related peptides. Peptides 27 953 PMID: 16515821

Gouarderes et al (2002) Quantitative autoradiographic distribution of NPFF₁ neuropeptide FF receptor in the rat brain and comparison with NPFF₂ receptor by using [¹²⁵I]YVP and [¹²⁵I]EYF as selective radioligands. Neurosci. 115 349

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关键词: Neuropeptide SF (mouse, rat), Neuropeptide SF (mouse, rat) supplier, NPFF1, NPFF2, agonists, Neuropeptides, FF, AF, Receptors, FF/AF, acid, sensing, ion, channel, 3, ASIC3, NeuropeptideSF, (mouse, rat), npffr1, npffr2, ASIC, Neuropeptide, Miscellaneous/Non-selective, Opioids, 3647, Tocris Bioscience

篇 Neuropeptide SF (mouse, rat) 的引用文献

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目前没有 Neuropeptide SF (mouse, rat) 的引用文献。