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Submit ReviewNeuropeptide Y (human, rat)
说明： Influences feeding and sexual behavior
别名： NPY (human,rat)
纯度： ≥95% (HPLC)
生物活性 for Neuropeptide Y (human, rat)
Neuropeptide Y (human, rat) is a widely distributed endogenous neuropeptide involved in the control of food intake, sexual behavior and blood pressure.
技术数据 for Neuropeptide Y (human, rat)
| 分子量 | 4271.7 |
| 公式 | C189H285N55O57S |
| 序列 |
YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY (Modifications: Tyr-36 = C-terminal amide) |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 90880-35-6 |
| PubChem ID | 24868177 |
| InChI Key | XKWCTHKJQNUFOQ-HRPSIEBRSA-N |
| Smiles | [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Neuropeptide Y (human, rat)
| 溶解性 | Soluble to 1 mg/ml in water |
产品说明书 for Neuropeptide Y (human, rat)
参考文献 for Neuropeptide Y (human, rat)
参考文献是支持产品生物活性的出版物。
Allen et al (1987) Molecular structure of mammalian neuropeptide Y: analysis by molecular cloning and computer-aided comparison with crystal structure of avian homologue. Proc.Natl.Acad.Sci.U.S.A. 84 2532 PMID: 3031687
Michel et al (1998) XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol.Rev. 50 143 PMID: 9549761
Minth et al (1984) Cloning, characterization, and DNA sequence of a human cDNA encoding neuropeptide tyrosine. Proc.Natl.Acad.Sci.U.S.A. 81 4577 PMID: 6589611
If you know of a relevant reference for Neuropeptide Y (human, rat), please let us know.
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关键词: Neuropeptide Y (human, rat), Neuropeptide Y (human, rat) supplier, Influences, feeding, sexual, behavior, Neuropeptide, Y, Receptors, NPY, agonists, NeuropeptideY, (human), neuropeptides, (human,, rat), 1153, Tocris Bioscience
4 篇 Neuropeptide Y (human, rat) 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Neuropeptide Y (human, rat) 的部分引用包括：
Acton et al (2019) Spinal Neuropeptide Y1 Receptor-Expressing Neurons Form an Essential Excitatory Pathway for Mechanical Itch. Cell Rep 28 625 PMID: 31315043
Alhadeff et al (2018) A Neural Circuit for the Suppression of Pain by a Competing Need State. Cell 173 140 PMID: 29570993
Businaro et al (2018) Platelet Lysate-Derived Neuropeptide y Influences Migration and Angiogenesis of Human Adipose Tissue-Derived Stromal Cells. Sci Rep 8 14365 PMID: 30254326
Singer et al (2013) Neuropeptide Y is produced by adipose tissue macrophages and regulates obesity-induced inflammation. PLoS One 8 e57929 PMID: 23472120
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Field Recording and Bath Application of NPY.
By
Aundrea Bartley on 01/05/2018
分析类型： In Vitro
种属： Mouse
Bath application of NPY to acute hippocampal slices and recorded field responses
We precoated the tubing with 0.1 mg/ml of BSA to prevent issues of NPY sticking to the tubing. BSA cannot be added directly to the recording solution because of issues that arise during oxygenation.
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.