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Submit ReviewNeurotensin
说明： Endogenous neurotransmitter and endocrine modulator
纯度： ≥95% (HPLC)
生物活性 for Neurotensin
Neurotensin is a brain and gastrointestinal peptide with many central and peripheral functions. Acts as neuromodulator of dopamine transmission and exerts potent hypothermic and analgesic effects. Peripherally, acts as a paracrine and endocrine modulator of the digestive tract and cardiovascular system.
技术数据 for Neurotensin
| 分子量 | 1672.94 |
| 公式 | C78H121N21O20 |
| 序列 |
XLYENKPRRPYIL (Modifications: X = Glp) |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| CAS Number | 39379-15-2 |
| PubChem ID | 90488724 |
| InChI Key | PCJGZPGTCUMMOT-IMEZQUPBSA-N |
| Smiles | CC[C@@H](C)[C@@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]1CCC(=O)N1)C(=O)N[C@@H](CC(C)C)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Neurotensin
| 溶解性 | Soluble to 0.70 mg/ml in water |
产品说明书 for Neurotensin
参考文献 for Neurotensin
参考文献是支持产品生物活性的出版物。
Binder et al (2001) Neurotensin and DA interactions. Pharmacol.Rev. 53 453 PMID: 11734615
Tyler-McMahon (2000) Neurotensin: peptide for the next millenium. Regul.Pept. 93 125 PMID: 11033059
Vincent et al (1999) Neurotensin and neurotensin receptors. TiPS 20 302 PMID: 10390649
If you know of a relevant reference for Neurotensin, please let us know.
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关键词: Neurotensin, Neurotensin supplier, Endogenous, neurotransmitter, endocrine, modulators, NT, Receptors, Neurotensin, agonists, 1909, Tocris Bioscience
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Neurotensin 的评论
平均评分: 5 (Based on 1 Review.)
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Neurotensin binding saturation and competition assays performed: Gives great publishable result.
By
Anonymous on 02/04/2019
种属： Human
Neurotensin binding Saturation Assay and a neurotensin binding Competition Assay were performed using the product. VICTOR™ Multi-label Reader has been used to measure the time-resolved fluorescence of each assay. The product gives great publishable results.
该领域的文献
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Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.