主页 / Product Type / 荧光成像 / Fluorescent Probes and Stains / Fluorescent Lipid Probes and Cell Membrane Stains / NR12S

NR12S

Cat. No. 7509 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Fluorogenic lipid membrane dye. Used for: staining lipid at the outer leaflet of vesicles and cell membranes, suitable for live cell imaging. Application: fluorescence microscopy
化学名： 3-((3-((9-(Diethylamino)-5-oxo-5H-benzo[a]phenoxazin-2-yl)oxy)propyl)(dodecyl)(methyl)ammonio)propane-1-sulfonate
纯度： ≥95% (HPLC)
说明书
引用文献
评论
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for NR12S

Key information: NR12S is a fluorogenic lipid membrane dye that stains the outer leaflet of lipid vesicles and cell membranes. Suitable for live cell imaging.

Used for: monitoring cholesterol and lipid order selectively at the outer leaflet of cell membranes.

Application: fluorescence microscopy.

Properties and Photophysical Data: NR12S is a conjugation of the Nile Red fluorophore with a long alkyl chain and a zwitterionic group, allowing strong interactions with the lipid membranes. Excitation and emission maxima (λ) are 554 nm and 627 nm in DMSO, respectively; quantum yield = 0.55.

Optical Data for NR12S

NR12S Dye Spectra
Emission Color Orange
λabs 554 nm
λem 627 nm
Quantum Yield (φ) 0.55
Closest Laser line 532 nm
Application Monitoring of Lipid Dynamics in Living Cells, Fluorescence Microscopy
Alternative For Nile Red

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

Spectral Viewer

技术数据 for NR12S

分子量 695.96
公式 C39H57N3O6S
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 1221739-85-0
PubChem ID 146165932
InChI Key MJGSHKTVWQIWAA-UHFFFAOYSA-N
Smiles CCCCCCCCCCCC[N+](CCCOC1=CC=C2C(C=C3OC4=CC(N(CC)CC)=CC=C4N=C3C2=C1)=O)(CCCS([O-])(=O)=O)C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for NR12S

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 6.96 10

制备储备液 for NR12S

以下数据基于产品分子量 695.96。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.1 mM 14.37 mL 71.84 mL 143.69 mL
0.5 mM 2.87 mL 14.37 mL 28.74 mL
1 mM 1.44 mL 7.18 mL 14.37 mL
5 mM 0.29 mL 1.44 mL 2.87 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for NR12S

参考文献是支持产品生物活性的出版物。

Kucherak et al (2010) Switchable nile red-based probe for cholesterol and lipid order at the outer leaflet of biomembranes. J.Am.Chem.Soc. 132 4907 PMID: 20225874

If you know of a relevant reference for NR12S, please let us know.

按标靶查看相关产品

关键词: NR12S, NR12S supplier, fluorogenic, probe, lipid, cholesterol, membranes, orange, dye, Nile, fluorescence, Fluorescent, Lipid, Probes, and, Cell, Membrane, Stains, 7509, Tocris Bioscience

篇 NR12S 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 NR12S 的引用文献。 您是否知道使用了 Tocris NR12S 的优秀论文？ 请告知我们.

NR12S 的评论

目前没有该产品的评论。 Be the first to review NR12S and earn rewards!

Have you used NR12S?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals