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说明： Inactive analog of m-3M3FBS (Cat. No. 1941)
化学名： 2,4,6-Trimethyl-N-[2-(trifluoromethyl)phenyl]benzenesulfonamide
纯度： ≥99% (HPLC)
生物活性 for o-3M3FBS
o-3M3FBS is an inactive analog of m-3M3FBS. Used as a negative control.
Active Analog also available.
化合物库 for o-3M3FBS
o-3M3FBS is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。
技术数据 for o-3M3FBS
| 分子量 | 343.36 |
| 公式 | C16H16F3NO2S |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 313981-55-4 |
| PubChem ID | 770820 |
| InChI Key | SKJJIFRWCCSXGL-UHFFFAOYSA-N |
| Smiles | CC1=CC(C)=C(C(C)=C1)S(=O)(=O)NC1=C(C=CC=C1)C(F)(F)F |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for o-3M3FBS
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| ethanol | 34.34 | 100 | |
| DMSO | 34.34 | 100 |
制备储备液 for o-3M3FBS
以下数据基于产品分子量 343.36。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.91 mL | 14.56 mL | 29.12 mL |
| 5 mM | 0.58 mL | 2.91 mL | 5.82 mL |
| 10 mM | 0.29 mL | 1.46 mL | 2.91 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.58 mL |
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产品说明书 for o-3M3FBS
参考文献 for o-3M3FBS
参考文献是支持产品生物活性的出版物。
Bae et al (2003) Identification of a compound that directly stimulates phospholipase C activity. Mol.Pharmacol. 63 1043 PMID: 12695532
If you know of a relevant reference for o-3M3FBS, please let us know.
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关键词: o-3M3FBS, o-3M3FBS supplier, Phospholipases, C, PLC, Esterases, activators, Phospholipase, 1942, Tocris Bioscience
6 篇 o-3M3FBS 的引用文献
引用文献是使用了 Tocris 产品的出版物。 o-3M3FBS 的部分引用包括：
Wilke et al (2014) Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors. Nat Commun 5 5540 PMID: 25420509
Szebenyi et al (2014) Increases in intracellular calcium via activation of potentially multiple phospholipase C isozymes in mouse olfactory neurons. Front Cell Neurosci 8 336 PMID: 25374507
Carim et al (2019) IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis. Curr Biol 29 775 PMID: 30799246
Semple-Rowland et al (2014) Activation of phospholipase C mimics the phase shifting effects of light on melatonin rhythms in retinal photoreceptors. PLoS One 8 e83378 PMID: 24386190
Krjukova et al (2004) Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. Br J Pharmacol 143 3 PMID: 15302681
Horowitz et al (2005) Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. PLoS One 126 243 PMID: 16129772
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