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Submit ReviewOctMAB
说明： Dynamin inhibitor
化学名： Octadecyltrimethylammonium bromide
生物活性 for OctMAB
OctMAB is a dynamin inhibitor (IC50 = 1.9 μM for dynamin I). Inhibits receptor-mediated endocytosis (IC50 = 16 μM). Displays similar activity to MitMAB (Cat. No. 4224).
技术数据 for OctMAB
| 分子量 | 392.5 |
| 公式 | C21H46BrN |
| 储存 | Desiccate at RT |
| CAS Number | 1120-02-1 |
| PubChem ID | 70708 |
| InChI Key | SZEMGTQCPRNXEG-UHFFFAOYSA-M |
| Smiles | CCCCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-] |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for OctMAB
参考文献 for OctMAB
参考文献是支持产品生物活性的出版物。
Quan et al (2007) Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II. Mol.Pharmacol. 72 1425 PMID: 17702890
Joshi et al (2010) The dynamin inhibitors MitMAB and OctMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells. Mol.Cancer Ther. 9 1995 PMID: 20571068
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关键词: OctMAB, OctMAB supplier, dynamin, I, II, inhibitors, inhibits, gtpase, endocytosis, OctMAB, Mitosis, Dynamin, 4225, Tocris Bioscience
1 篇 OctMAB 的引用文献
引用文献是使用了 Tocris 产品的出版物。 OctMAB 的部分引用包括：
Ford et al (2018) Chlamydia exploits filopodial capture and a macropinocytosis-like pathway for host cell entry. PLoS Pathog 14 e1007051 PMID: 29727463
OctMAB 的评论
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