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PAF (C16)

Cat. No. 2940 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Endogenous platelet-activating factor (PAF)
别名： Platelet-activating factor
化学名： (7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium-4-oxide
说明书
引用文献
评论 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for PAF (C16)

PAF (C16) is an endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.

技术数据 for PAF (C16)

分子量 523.68
公式 C26H54NO7P
储存 Store at -20°C
CAS Number 74389-68-7
PubChem ID 108156
InChI Key HVAUUPRFYPCOCA-AREMUKBSSA-N
Smiles CC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COCCCCCCCCCCCCCCCC)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for PAF (C16)

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 52.37 100

制备储备液 for PAF (C16)

以下数据基于产品分子量 523.68。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 1.91 mL 9.55 mL 19.1 mL
5 mM 0.38 mL 1.91 mL 3.82 mL
10 mM 0.19 mL 0.95 mL 1.91 mL
50 mM 0.04 mL 0.19 mL 0.38 mL

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产品说明书 for PAF (C16)

分析证书/产品说明书
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化学品安全技术说明书

参考文献 for PAF (C16)

参考文献是支持产品生物活性的出版物。

Oda et al (1985) Molecular species of platelet-activating factor generated by human neutrophils challenged with ionophore A23187. J.Immunol. 134 1090 PMID: 3917470

Archer et al (1988) Actions of platelet activating factor (PAF) homologues and their combinations on neutrophil chemokinesis and cutaneous inflammatory responses in man. J.Invest.Dermatol. 91 82 PMID: 3385217

Handa et al (1991) Vasorelaxant effect of C16-PAF and C18-PAF on renal blood flow and systemic blood pressure in the anesthetized rat. Life Sci. 49 747 PMID: 1875784

If you know of a relevant reference for PAF (C16), please let us know.

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关键词: PAF (C16), PAF (C16) supplier, Endogenous, platelet-activating, factor, PAF, Receptors, Platelet-activating, Factor, (PAF), 2940, Tocris Bioscience

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Platelet activating factor (PAF).
By Anonymous on 05/02/2018
分析类型： In Vitro
种属： Human
细胞系/组织： microglia

Platelet activating factor (PAF) at 100nM induced a biphasic calcium response in microglia culture. Initial release from internal source and subsequent a sustained influx.