Pancreatic Polypeptide (human)

Cat. No. 1154 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： NPY Y₄ agonist; involved in gastrointestinal tract function

纯度： ≥95% (HPLC)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Pancreatic Polypeptide (human)

Pancreatic Polypeptide (human) is an endogenous high affinity agonist for human NPY Y₄ receptor (K_i = 0.056 nM). Believed to play an important role in the function of the gastrointestinal tract.

技术数据 for Pancreatic Polypeptide (human)

分子量	4181.7
公式	C₁₈₅H₂₈₇N₅₃O₅₄S₂
序列	APLEPVYPGDNATPEQMAQYAADLRRYINMLTRPRY (Modification: Tyr-36 = C-terminal amide)
储存	Store at -20°C
纯度	≥95% (HPLC)
CAS Number	75976-10-2
PubChem ID	24868176
InChI Key	HFDKKNHCYWNNNQ-YOGANYHLSA-N
Smiles	[H]N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Pancreatic Polypeptide (human)

溶解性	Soluble to 0.70 mg/ml in water

产品说明书 for Pancreatic Polypeptide (human)

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Pancreatic Polypeptide (human)

参考文献是支持产品生物活性的出版物。

Bard et al (1995) Cloning and functional expression of a human Y₄ subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY. J.Biol.Chem. 270 26762 PMID: 7592911

Gehlert (1998) Multiple receptors for the pancreatic polypeptide (PP-fold) family: physiological implications. Proc.Soc.Exp.Biol.Med. 218 7 PMID: 9572148

Michel et al (1998) XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol.Rev. 50 143 PMID: 9549761

If you know of a relevant reference for Pancreatic Polypeptide (human), please let us know.

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关键词: Pancreatic Polypeptide (human), Pancreatic Polypeptide (human) supplier, NPY, Y4, agonist, involved, gastrointestinal, tract, function, Neuropeptide, Y, Receptors, neuropeptides, 1154, Tocris Bioscience

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