Parathyroid hormone (1-34) (human)

Pricing Availability   Qty
说明: Parathyroid hormone (PTH) receptor agonist
别名: PTH 1-34,hPTH (1-34),Teriparatide
纯度: ≥95% (HPLC)
说明书
引用文献 (2)
评论

生物活性 for Parathyroid hormone (1-34) (human)

Parathyroid hormone (1-34) (human) is a human parathyroid hormone (hPTH) peptide fragment; contains the 34 N-terminal residues of hPTH. Agonist at parathyroid 1 (PTH1) and parathyroid 2 (PTH2) receptors.

技术数据 for Parathyroid hormone (1-34) (human)

分子量 4117.75
公式 C181H291N55O51S2
序列 SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 52232-67-4
PubChem ID 16132393
InChI Key OGBMKVWORPGQRR-UMXFMPSGSA-N
Smiles [H]N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Parathyroid hormone (1-34) (human)

溶解性 Soluble to 0.40 mg/ml in water

产品说明书 for Parathyroid hormone (1-34) (human)

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参考文献 for Parathyroid hormone (1-34) (human)

参考文献是支持产品生物活性的出版物。

Dobnig and Turner (1997) The effects of programmed administration of human parathyroid hormone fragment (1-34) on bone histomorphometry and serum chemistry in rats. Endocrinology 138 4607 PMID: 9348185

Manabe et al (2007) Human parathyroid hormone (1-34) accelerates natural fracture healing process in the femoral osteotomy model of cynomolgus monkeys. Bone 40 1475 PMID: 17369013

Niall et al (1974) The amino acid sequence of the amino-terminal 37 residues of human parathyroid hormone. Proc.Natl.Acad.Sci. 71 384


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关键词: Parathyroid hormone (1-34) (human), Parathyroid hormone (1-34) (human) supplier, Parathyroid, hormone, PTH, receptors, agonists, PTH134, 1-34, teriparatide, (1-34), hPTH, Teriparatide, Hormone, Receptors, 3011, Tocris Bioscience

⚠ WARNING: This product can expose you to chemicals including Teriparatide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

2 篇 Parathyroid hormone (1-34) (human) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Parathyroid hormone (1-34) (human) 的部分引用包括:

Li et al (2019) TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis. Nat Commun 10 2795 PMID: 31243287

Reinisch et al (2017) Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice. Nat Protoc 12 2169 PMID: 28933777


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