Parathyroid Hormone Receptors
Parathyroid hormone (PTH) receptors are a group of Gs-protein-coupled receptors, currently divided into two subtypes: PTH1 and PTH2. Each subtype has a distinct distribution and mediates different biological actions. PTH1 is ubiquitously expressed.
Parathyroid Hormone Receptor Agonists |
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|---|---|
| Cat. No. | Product Name / Activity |
| 6301 | Parathyroid hormone (1-34) (rat) |
| Parathyroid hormone (PTH) receptor agonist | |
| 3011 | Parathyroid hormone (1-34) (human) |
| Parathyroid hormone (PTH) receptor agonist | |
Parathyroid hormone (PTH) receptors are a group of Gs-protein-coupled receptors, currently divided into two subtypes: PTH1 and PTH2. Each subtype has a distinct distribution and mediates different biological actions. PTH1 is ubiquitously expressed, but is found at particularly high levels in skeletal muscle and the kidneys.
PTH1 is involved in calcium and phosphate homeostasis and has a role in chondrocyte regulation. PTH2 expression is limited to the brain and testes. Its actions are proposed to include nociception and regulation of pituitary hormone secretion. The human genes encoding the PTH1 and PTH2 receptors are located on chromosomes 3p22-21.1 and 2q33 respectively.