主页 / Product Type / 荧光成像 / Fluorescent Probes and Stains / Fluorescent Amyloid β Probes / PE 154

PE 154

Cat. No. 4086 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4086 has been discontinued.

说明： Targets and labels βamyloid plaques in histochemical analysis
化学名： 4-[[[7-(Diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid 2-(1,2,3,4-tetrahydro-9-acridinyl)hydrazide
纯度： ≥97% (HPLC)
说明书
引用文献 (1)
评论
文献 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for PE 154

PE 154 is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50 values are 280 pM and 16 nM respectively). Targets and labels β-amyloid plaques in histochemical analysis.

技术数据 for PE 154

分子量 589.68
公式 C35H35N5O4
储存 Store at +4°C
纯度 ≥97% (HPLC)
CAS Number 1192750-33-6
PubChem ID 90488911
InChI Key CYZIIGRHLSZNAV-SGWCAAJKSA-N
Smiles O=C(CC4=CC=C(N/C=C5/C(OC(C=C(N(CC)CC)C=C6)=C6C5=O)=O)C=C4)NNC2=C3C(CCCC3)=NC1=CC=CC=C12

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for PE 154

参考文献是支持产品生物活性的出版物。

Kacza et al (2010) In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles. Eur.J.Neurosci. 31 99 PMID: 20092557

Elsinghorst et al (2009) A gorge-spanning, high-affinity cholinesterase inhibitor to explore β-amyloid plaques. Org.Biomol.Chem. 7 3940 PMID: 19763296

按标靶查看相关产品

关键词: PE 154, PE 154 supplier, PE154, fluorescent, AChE, inhibitor, beta, amyloid, plaque, probe, probes, b-amyloid, acetylcholinesterase, inhibitors, inhibits, fluorescence, histochemistry, staining, labelling, Cholinesterases, Fluorescent, Amyloid, B, Probes, Enzyme, and, Substrates, 4086, Tocris Bioscience

1 篇 PE 154 的引用文献

引用文献是使用了 Tocris 产品的出版物。 PE 154 的部分引用包括：

Zemkova et al (2011) NE causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+. Endocrinology 152 3842 PMID: 21828176

PE 154 的评论

目前没有该产品的评论。 Be the first to review PE 154 and earn rewards!

Have you used PE 154?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals