Perhexiline maleate

Name: Perhexiline maleate
Brand: Tocris Bioscience
SKU: 5166
Rating: 5 (1 reviews)

Cat. No. 5166 1 次引用 1 条评论提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor

化学名： 2-(2,2-Dicyclohexylethyl)piperidine maleate

纯度： ≥99% (HPLC)

说明书

引用文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Perhexiline maleate

Perhexiline maleate is a carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor. Inhibits palmitate oxidation in rat cardiomyocytes and increases cardiac efficiency in isolated rat hearts. Antianginal.

化合物库 for Perhexiline maleate

Perhexiline maleate is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for Perhexiline maleate

分子量	393.56
公式	C₁₉H₃₅N.C₄H₄O₄
储存	Store at +4°C
纯度	≥99% (HPLC)
CAS Number	6724-53-4
PubChem ID	5284439
InChI Key	JDZOTSLZMQDFLG-BTJKTKAUSA-N
Smiles	OC(\C=C/C(O)=O)=O.C1(CC(C3CCCCC3)C2CCCCC2)NCCCC1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Perhexiline maleate

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	DMSO	39.36	100
	ethanol	7.87	20

制备储备液 for Perhexiline maleate

以下数据基于产品分子量 393.56。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	2.54 mL	12.7 mL	25.41 mL
5 mM	0.51 mL	2.54 mL	5.08 mL
10 mM	0.25 mL	1.27 mL	2.54 mL
50 mM	0.05 mL	0.25 mL	0.51 mL

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产品说明书 for Perhexiline maleate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Perhexiline maleate

参考文献是支持产品生物活性的出版物。

Kennedy et al (1996) Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiod. Biochem.Pharmacol. 52 273 PMID: 8694852

Unger et al (2005) Dissociation between metabolic and efficiency effects of perhexiline in normoxic rat myocardium. J.Cardiovasc.Pharmacol. 46 849 PMID: 16306812

Yin et al (2013) Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome. J.Mol.Cell.Cardiol. 55 27 PMID: 23277191

If you know of a relevant reference for Perhexiline maleate, please let us know.

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关键词: Perhexiline maleate, Perhexiline maleate supplier, Carnitine, palmitoyltransferase-1/2, CPT1, CPT2, antianginal, cardiac, inhibits, inhibitors, Other, Transferases, 5166, Tocris Bioscience

1 篇 Perhexiline maleate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Perhexiline maleate 的部分引用包括：

Louis-Philippe et al (2020) Microglial metabolic flexibility supports immune surveillance of the brain parenchyma. Nat Commun 11 1559 PMID: 32214088

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