Peroxy Orange 1

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10 mg / $335Ships in 5-7 Business Days
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说明: Fluorescent hydrogen peroxide indicator
别名: PO1
化学名: 2',3',6',7'-Tetrahydro-12'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-spiro[isobenzofuran-1(3H),9'-[1H,5H,9H]xantheno[2,3,4-ij]quinolizin]-3-one
说明书
引用文献 (2)
评论
文献 (1)

生物活性 for Peroxy Orange 1

Peroxy Orange 1 is a fluorescent probe for imaging hydrogen peroxide (H2O2); cell permeable. Displays an orange intracellular fluorescence in response to H2O2 signals produced in RAW 264.7 macrophages and A431 cells during immune response and growth factor stimulation, respectively. Excitation wavelength 543 nm, emission between 545 and 750 nm.

许可信息

Sold under license from the Regents of the University of California

技术数据 for Peroxy Orange 1

分子量 521.41
公式 C32H32BNO5
储存 Store at -20°C
CAS Number 1199576-10-7
PubChem ID 44546671
InChI Key KNTNXZHHCPNNGB-UHFFFAOYSA-N
Smiles O=C(O1)C2=C(C=CC=C2)C31C4=CC5=C6C(CCCN6CCC5)=C4OC7=C3C=CC(B8OC(C)(C)C(C)(C)O8)=C7

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Peroxy Orange 1

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 5.21 10

制备储备液 for Peroxy Orange 1

以下数据基于产品分子量 521.41。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.1 mM 19.18 mL 95.89 mL 191.79 mL
0.5 mM 3.84 mL 19.18 mL 38.36 mL
1 mM 1.92 mL 9.59 mL 19.18 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

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产品说明书 for Peroxy Orange 1

分析证书/产品说明书
选择另一批次:

参考文献 for Peroxy Orange 1

参考文献是支持产品生物活性的出版物。

Dickinson et al (2010) A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cells. J.Am.Chem.Soc. 132 5906 PMID: 20361787

Dickinson et al (2011) Chemistry and biology of reactive oxygen species in signaling or stress responses. Nat.Chem.Biol. 7 504 PMID: 21769097

Woolley et al (2012) H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling. PLoS ONE 7 PMID: 22807997


If you know of a relevant reference for Peroxy Orange 1, please let us know.

关键词: Peroxy Orange 1, Peroxy Orange 1 supplier, Fluorescent, probe, hydrogen, peroxide, H2O2, po1, po-1, peroxyorange, orange, immune, growth, factor, excitation, wavelength, emission, PO1, Cell, Indicators, and, Sensors, 4944, Tocris Bioscience

2 篇 Peroxy Orange 1 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Peroxy Orange 1 的部分引用包括:

Young Taek et al (2016) A single gene of a commensal microbe affects host susceptibility to enteric infection. Nat Commun 7 11606 PMID: 27173141

Jeong et al (2017) Prdx1 (peroxiredoxin 1) deficiency reduces cholesterol efflux via impaired macrophage lipophagic flux. Autophagy 14 120 PMID: 28605287


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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。


Fluorescent Dyes and Probes Research Product Guide

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