Phen Green SK diacetate

Pricing Availability   Qty
说明: Heavy metal ion indicator, membrane permeable
化学名: 3',6'-Bis(acetyloxy)-2',7'-dichloro-3-oxo-N-1,10-phenanthrolin-5-yl-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxamide
纯度: ≥90% (HPLC)
说明书
引用文献
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生物活性 for Phen Green SK diacetate

Phen Green SK diacetate is a fluorescent heavy metal ion indicator that can be used to detect various metal ions including Cu2+, Cu+, Fe2+, Hg2+, Pb2+, Cd2+, Zn2+ and Ni2+. Excitation and emission maxima (λ) are 507 and 532 nm, respectively. Intracellular Phen Green SK diacetate fluorescence is quenched upon reaction with metal ions. This product is cell permeable.

It is recommended to prepare stock solutions in DMSO.

Optical Data for Phen Green SK diacetate

λabs 507 nm
λem 532 nm
Extinction Coefficient (ε) 40000 M-1cm-1
Cell Permeable Yes
Application Fluorescence Microscopy, Flow Cytometry

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技术数据 for Phen Green SK diacetate

分子量 706.49
公式 C37H21Cl2N3O8
储存 Store at -20°C
纯度 ≥90% (HPLC)
CAS Number 234075-45-7
PubChem ID 137700453
InChI Key INOXUAMBIQQWOK-UHFFFAOYSA-N
Smiles O=C1OC2(C3=CC=C(C(NC4=CC5=CC=CN=C5C6=C4C=CC=N6)=O)C=C13)C7=CC(Cl)=C(C=C7OC8=CC(OC(C)=O)=C(C=C82)Cl)OC(C)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Phen Green SK diacetate

参考文献 for Phen Green SK diacetate

参考文献是支持产品生物活性的出版物。

Shen et al (2022) Geniposide possesses the protective effect on myocardial injury by inhibiting oxidative stress and ferroptosis via activation of the Grsf1/GPx4 Axis. Front.Pharmacol. 13 879870 PMID: 35600863

Kim et al (2006) Calibration of Phen Green for use as a Cu(I)-selective fluorescent indicator. Anal.Chim.Acta 575 223 PMID: 17723595

Lu et al (2022) Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma. J.Exp.Clin.Cancer Res. 41 3 PMID: 34980204


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