PM 102

Name: PM 102
Brand: Tocris Bioscience
SKU: 4034

Cat. No. 4034 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4034 has been discontinued.

View all Cell Adhesion Molecules products.

说明： Antagonist of heparin (Cat. No. 2812)

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性 for PM 102

PM 102 is a peptide that reverses the anticoagulant effect of heparin (Cat. No. 2812). Potently binds heparin (K_d = 36 nM in vitro).

许可信息

Sold under license

技术数据 for PM 102

分子量	5830
公式	C₂₃₅H₄₂₅N₁₁₁O₆₄
序列	AEARARRAAARAARRAKK(AEARARRAAARAARRA)PX(AEARARRAAARAARRA)EN (Modifications: Ala-1 = N-terminal Ac, Ala-19 = ε-Ac, X-36 = Dpr, Ala-37 = β-Ac, Glu-53 = C-terminal Amide)
储存	Store at -20°C
CAS Number	1234564-95-4
PubChem ID	16130295
InChI Key	ZPNFWUPYTFPOJU-LPYSRVMUSA-N
Smiles	C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(C)=O)C(=O)N1CCC[C@H]1C(=O)NC(CNC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for PM 102

分析证书/产品说明书

化学品安全技术说明书

参考文献 for PM 102

参考文献是支持产品生物活性的出版物。

Cushing et al (2010) Reversal of heparin-induced increases in aPTT in the rat by PM102, a novel he. antagonist. Eur.J.Pharmacol. 635 165 PMID: 20307530

Shenoy et al (1999) Development of he. antagonists with focused biological activity. Curr.Pharmaceut.Des. 5 965

Schick et al (2004) Novel concatameric heparin-binding peptides reverse he. and low-molecular-weight he. anticoagulant activities in patient plasma in vitro and in rats in vivo. Blood 103 4

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关键词: PM 102, PM 102 supplier, PM102, heparin, antagonists, anticoagulants, HepArrest, Cell, Adhesion, Molecules, 4034, Tocris Bioscience

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