主页 / Product Type / 荧光成像 / Fluorescent Probes and Stains / Fluorescent Amyloid β Probes / QM-FN-SO3

QM-FN-SO3

Cat. No. 7958 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Blood-brain barrier penetrant, NIR aggregation-induced emission active probe of amyloid β plaques. Used for: in vitro, in situ and in vivo imaging of amyloid β plaques. Application: confocal microscopy and in vivo imaging
化学名： Sodium 3-(4-(Dicyanomethylene)-2-(2-(5-(4-(dimethylamino)phenyl)thiophen-2-yl)vinyl)quinolin-1(4H)-yl)propane-1-sulfonate
纯度： ≥95% (HPLC)
说明书
引用文献
评论
文献 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for QM-FN-SO3

Key information: QM-FN-SO3 is a near-infrared (NIR) aggregation-induced emission active probe for in vivo imaging of amyloid β (Aβ) plaques. Blood brain barrier penetrant.

Used for: detection of Aβ plaques in vitro, in situ and in vivo.

Application: confocal microscopy and in vivo imaging.

Properties and Photophysical Data: QM-FN-SO3 shows high binding affinity, ultra-high sensitivity, low signal-to-noise ratio, and large stokes shift (170 nm) reducing excitation light-induced self-quenching. Excitation and emission maxima (λ) are 488 nm and 680 nm, respectively.

Optical Data for QM-FN-SO3

QM-FN-SO3 Dye Spectra
λabs 488 nm
λem 680 nm
Cell Permeable Yes
Application Confocal imaging of amyloid-beta plaques, in vitro and in vivo

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

Spectral Viewer

技术数据 for QM-FN-SO3

分子量 564.65
公式 C29H25N4O3S2.Na
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 2316820-94-5
PubChem ID 154727758
InChI Key WYMGXQAGHDNQOV-UEIGIMKUSA-M
Smiles CN(C)C1=CC=C(C=C1)C2=CC=C(S2)/C=C/C(N(CCCS(=O)([O-])=O)C3=C/4C=CC=C3)=CC4=C(C#N)/C#N.[Na+]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for QM-FN-SO3

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 28.23 50
water 11.29 20

制备储备液 for QM-FN-SO3

以下数据基于产品分子量 564.65。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.5 mM 3.54 mL 17.71 mL 35.42 mL
2.5 mM 0.71 mL 3.54 mL 7.08 mL
5 mM 0.35 mL 1.77 mL 3.54 mL
25 mM 0.07 mL 0.35 mL 0.71 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

参考文献 for QM-FN-SO3

参考文献是支持产品生物活性的出版物。

Yan et al (2023) Preparation of near-infrared AIEgen-active fluorescent probes for mapping amyloid-β plaques in brain tissues and living mice. Nat.Protoc. 18 1316 PMID: 36697872

Fu et al (2019) Rational design of near-infrared aggregation-induced-emission-active probes: in situ mapping of amyloid-β plaques with ultrasensitivity and high-fidelity. J.Am.Chem.Soc. 141 3171 PMID: 30632737

Su et al (2022) Strategic design of amyloid-β species fluorescent probes for Alzheimer's disease. ACS Chem.Neurosci. 13 540 PMID: 35132849

If you know of a relevant reference for QM-FN-SO3, please let us know.

按标靶查看相关产品

关键词: QM-FN-SO3, QM-FN-SO3 supplier, Alzheimer's, disease, alzheimers, amyloid-β, species, near-infrared, NIR, fluorescent, probes, diagnosis, AB, amyloid-beta, beta-amyloid, aggregates, plaques, amyloidβ, amyloid, beta, brain, penetrant, peptides, Fluorescent, Amyloid, B, Probes, Beta, Peptides, 7958, Tocris Bioscience

篇 QM-FN-SO3 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 QM-FN-SO3 的引用文献。 您是否知道使用了 Tocris QM-FN-SO3 的优秀论文？ 请告知我们.

QM-FN-SO3 的评论

目前没有该产品的评论。 Be the first to review QM-FN-SO3 and earn rewards!

Have you used QM-FN-SO3?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals