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Submit Review(R)-Citalopram oxalate
说明： Enantiomer of escitalopram oxalate (Cat. No. 1427)
化学名： (-)-(R)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
纯度： ≥98% (HPLC)
生物活性 for (R)-Citalopram oxalate
(R)-Citalopram oxalate is an enantiomer of escitalopram oxalate. Postulated to allosterically modulate the affinity of the S-enantiomer.
Racemate and S-enantiomer also available.
技术数据 for (R)-Citalopram oxalate
| 分子量 | 414.43 |
| 公式 | C20H21FN2O.C2H2O4 |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 219861-53-7 |
| PubChem ID | 45038690 |
| InChI Key | KTGRHKOEFSJQNS-VEIFNGETSA-N |
| Smiles | FC(C=C3)=CC=C3[C@@]1(CCCN(C)C)OCC2=C1C=CC(C#N)=C2.OC(C(O)=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for (R)-Citalopram oxalate
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 20.72 | 50 | |
| DMSO | 41.44 | 100 |
制备储备液 for (R)-Citalopram oxalate
以下数据基于产品分子量 414.43。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.41 mL | 12.06 mL | 24.13 mL |
| 5 mM | 0.48 mL | 2.41 mL | 4.83 mL |
| 10 mM | 0.24 mL | 1.21 mL | 2.41 mL |
| 50 mM | 0.05 mL | 0.24 mL | 0.48 mL |
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产品说明书 for (R)-Citalopram oxalate
参考文献 for (R)-Citalopram oxalate
参考文献是支持产品生物活性的出版物。
Jacquot et al (2007) Escitalopram and citalopram: the unexpected role of the R-enantiomer. Encephale 33 179 PMID: 17675913
Sánchez et al (2006) The pharmacology of cital. enantiomers: the antagonism by R-citalopram on the effect of S-citalopram. Basic & Clinical Pharmacology & Toxicology 99 91 PMID: 16918708
If you know of a relevant reference for (R)-Citalopram oxalate, please let us know.
关键词: (R)-Citalopram oxalate, (R)-Citalopram oxalate supplier, Enantiomers, escitalopram, oxalate, 5-HT, reuptake, modulators, allosteric, SERT, 5-hydroxytryptamine, monoamine, neurotransmitters, citalopram, depression, Transporters, 5763, Tocris Bioscience
1 篇 (R)-Citalopram oxalate 的引用文献
引用文献是使用了 Tocris 产品的出版物。 (R)-Citalopram oxalate 的部分引用包括：
Henry A et al (2020) Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning. Cell 183 1986-2002.e26 PMID: 33333022
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5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.