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Rifampicin

Cat. No. 4121 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Pregnane X receptor agonist; antibiotic
别名： Rifampin
化学名： 3-[[(4-Methyl-1-piperazinyl)imino]methyl]-rifamycin
纯度： ≥95% (HPLC)
说明书
引用文献
评论 (1)
文献 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for Rifampicin

Rifampicin is an antibiotic; inhibits bacterial RNA polymerase. Prototypical activator of the pregnane X receptor (PXR).

技术数据 for Rifampicin

分子量 822.94
公式 C43H58N4O12
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 13292-46-1
PubChem ID 5381226
InChI Key FZYOVNIOYYPUPY-ZTWDQPHTSA-N
Smiles CN(CC1)CCN1/N=C/C2=C(O)C3=C(C4=O)C5=C(C)C(O)=C3C(O)=C2NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@H]([C@H]([C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)/C=C/O[C@@]4(C)O5)O)C)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Rifampicin

参考文献是支持产品生物活性的出版物。

Wehrli (1983) Rifampin: mechanisms of action and resistance. Rev.Infect.Dis. 5 S407 PMID: 6356275

Moore et al (2000) Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. J.Biol.Chem. 275 15122 PMID: 10748001

Artsimovitch et al (2005) Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell 122 351 PMID: 16096056

Hu et al (2010) Pregnane X receptor is SUMOylated to repress the inflammatory response. J.Pharmacol.Exp.Ther. 335 342 PMID: 20719936

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关键词: Rifampicin, Rifampicin supplier, bacterial, RNA, polymerase, antibiotics, inhibitors, inhibits, pregnane, x, receptors, PXR, activators, Rifampin, Antibiotics, Pregnane, X, Receptor, DNA,, and, Protein, Synthesis, 4121, Tocris Bioscience

⚠ WARNING: This product can expose you to chemicals including Rifampin, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

篇 Rifampicin 的引用文献

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Rifampicin resisistance in E.coli cells was studied.
By Anonymous on 12/03/2018
分析类型： In Vitro
种属： Human

In our lab rifampicin resisistance in E.coli cells was studied.To assess the level of antibiotic resistance, the minimum inhibitory concentration (MICs) of rifampicin in the non-mutated strain and mutated strain were compared.

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