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RWJ 50271

Cat. No. 4227 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

4227 has been discontinued.

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说明： Inhibitor of LFA-1/ICAM mediated cell adhesion
化学名： N-(3-Hydroxypropyl)-5-methyl-1-[-4-[3-(trifluoromethyl)phenyl)]-2-thiazolyl]-1H-pyrazole-4-carboxamide
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论
文献 (2)
生物活性 技术数据 说明书 参考文献

生物活性 for RWJ 50271

RWJ 50271 is a selective inhibitor of LFA-1 (lymphocyte function-associated antigen-1) adhesion to soluble intercellular adhesion molecule (sICAM) (IC50 = 5 μM in HL60 cells).

技术数据 for RWJ 50271

分子量 410.41
公式 C18H17F3N4O2S
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 162112-37-0
PubChem ID 9953357
InChI Key HOFGTYCLOKDAES-UHFFFAOYSA-N
Smiles CC1=C(C(NCCCO)=O)C=NN1C2=NC(C3=CC(C(F)(F)F)=CC=C3)=CS2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for RWJ 50271

参考文献是支持产品生物活性的出版物。

Sanfilippo et al (1995) Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion. J.Med.Chem. 38 1057 PMID: 7707308

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关键词: RWJ 50271, RWJ 50271 supplier, RWJ50271, inhibitors, inhibits, LFA-1/ICAM-1, adhesion, sICAM, lymphocyte, function-associated, antigen-1, Integrins, Cell, Adhesion, Molecules, 4227, Tocris Bioscience

1 篇 RWJ 50271 的引用文献

引用文献是使用了 Tocris 产品的出版物。 RWJ 50271 的部分引用包括：

Takizawa (2017) Bone marrow-derived mesenchymal stem cells propagate immunosuppressive/anti-inflammatorymacrophages in cell-to-cell contact-independent and dependent manners under hypoxic culture. Exp Cell Res 358 441 PMID: 28712928

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