SBP1

Discontinued Product

7233 has been discontinued.

View all ACE2 products.
说明: ACE2 derived peptide; binds SARS-CoV-2 spike protein receptor binding domain
纯度: ≥95% (HPLC)
说明书
引用文献
评论

生物活性 for SBP1

SBP1 is a human ACE2 receptor-derived 23-amino acid peptide. Binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication).

Please note - unpublished, in-house data suggests approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than reported by Zhang et al.

技术数据 for SBP1

分子量 2802.05
公式 C127H185N31O41
序列 IEEQAKTFLDKFNHEAEDLFYQS

(Modifications: Ser-23 = C-terminal amide)

储存 Store at -20°C
纯度 ≥95% (HPLC)
InChI Key VTVUOJBJFPPIBF-SDBILGLNSA-N
Smiles O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(N)=O)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for SBP1

分析证书/产品说明书
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参考文献 for SBP1

参考文献是支持产品生物活性的出版物。

Zhang et al (2020) Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD. BioRxiv - Paper not yet peer reviewed

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关键词: SBP1, SBP1 supplier, spike, binding, protein, SARS-CoV-2, receptor, domain, RBD, COVID-19, severe, acute, respiratory, syndrome, ACE2, peptide, fluorescent, FITC, 7233, Tocris Bioscience

篇 SBP1 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 SBP1 的引用文献。

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