主页 / 药理学 / GPCRs / 7-TM Receptors / Prostanoid Receptors / Prostanoid Receptor Antagonists / SC 19220

SC 19220

Cat. No. 1206 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Selective EP1 receptor antagonist
化学名： 8-Chloro-dibenzo(Z)[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-acetylhydrazide
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for SC 19220

SC 19220 is a selective EP1 receptor antagonist (IC50 = 6.7 μM for inhibition of [3H]-PGE2 binding to EP1 transfected COS cells).

化合物库 for SC 19220

SC 19220 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for SC 19220

分子量 331.76
公式 C16H14ClN3O3
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 19395-87-0
PubChem ID 4336830
InChI Key KNURFLJTOUGOOQ-UHFFFAOYSA-N
Smiles CC(=O)NNC(=O)N1CC2=C(OC3=CC=C(Cl)C=C13)C=CC=C2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for SC 19220

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
ethanol 8.29 25 温和加热
DMSO 33.18 100

制备储备液 for SC 19220

以下数据基于产品分子量 331.76。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.01 mL 15.07 mL 30.14 mL
5 mM 0.6 mL 3.01 mL 6.03 mL
10 mM 0.3 mL 1.51 mL 3.01 mL
50 mM 0.06 mL 0.3 mL 0.6 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

产品说明书 for SC 19220

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for SC 19220

参考文献是支持产品生物活性的出版物。

Botella et al (1995) Receptor subtypes involved in dual effects induced by prostaglandin E2 in circular smooth muscle from dog colon. J.Pharmacol.Exp.Ther. 273 1008 PMID: 7791070

Funk et al (1993) Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype. J.Biol.Chem. 268 26767 PMID: 8253813

Sanner (1972) Dibenzoxazepine hydrazides as prostaglandin antagonists. Intra-Science Chem.Rept. 6 1

If you know of a relevant reference for SC 19220, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Prostanoid Receptor Antagonists

关键词: SC 19220, SC 19220 supplier, Selective, EP1, receptor, antagonist, Receptors, Prostanoids, prostaglandins, prostacyclins, eicosanoids, SC19220, Prostanoid, 1206, Tocris Bioscience

1 篇 SC 19220 的引用文献

引用文献是使用了 Tocris 产品的出版物。 SC 19220 的部分引用包括：

Passafaro et al (2011) Cholinergic Autoantibodies from Primary Sjögren's Syndrome Inhibit Mucin Production via Phospholipase C and Cyclooxygenase-2 In the Rat Submandibular Gland. Neuropharmacology 8 138 PMID: 22013477

您是否知道使用了 Tocris SC 19220 的优秀论文？ 请告知我们.

SC 19220 的评论

目前没有该产品的评论。 Be the first to review SC 19220 and earn rewards!

Have you used SC 19220?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review