SCOTfluor glucose probe 510

Cat. No. 7447 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Fluorescent glucose probe

化学名： 2-Deoxy-2-[(7-nitro-2,1,3-benzoselenadiazol-4-yl)amino]-D-glucose

纯度： ≥98% (HPLC)

文献 (1)

生物活性 Scientific Data 技术数据溶解性计算器说明书参考文献

生物活性 for SCOTfluor glucose probe 510

SCOTfluor glucose probe 510 is a fluorescent probe for visualizing glucose uptake in vivo. It can be multiplexed with BFP and GFP. Excitation and emission maxima (λ) are 490 and 605 nm, respectively.

Scientific Data

Confocal Microscopy

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Application of SCOTfluor glucose probe 510 in HeLa cells. Fluorescence microscopy image of GLUT4-EGFP HeLa cells treated with SCOTfluor glucose probe 510 (100 μm). Colors: green (GLUT4-EGFP), red (SCOTfluor glucose probe 510), blue: Hoechst 33342 (Catalog # 5117). Image kindly provided by Prof. Marc Vendrell, acquired by Dr Sam Benson, Centre for Inflammation Research, University of Edinburgh.

In vivo Imaging

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Application of SCOTfluor glucose probe 510 in zebrafish embryos. In vivo images of zebrafish embryos (28 h post fertilization) after injection of SCOTfluor glucose probe 510 (50 pmol) to the yolk sac in wildtype zebrafish (left) or zebrafish injected at one cell stage with 4.2 ng anti-sense glu2 morpholino (right). Image kindly provided by Prof. Marc Vendrell, acquired by Dr Yi Feng, Centre for Inflammation Research, University of Edinburgh.

许可信息

Sold under license from the University of Edinburgh

Optical Data for SCOTfluor glucose probe 510

Emission Color	Orange
λ_abs	490 nm
λ_em	605 nm
Closest Laser line	488 nm
Cell Permeable	Yes
Application	Fluorescence Microscopy, Confocal Microscopy, in vivo Imaging

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectral Viewer

技术数据 for SCOTfluor glucose probe 510

分子量	405.23
公式	C₁₂H₁₄N₄O₇Se
储存	Store at -20°C
纯度	≥98% (HPLC)
CAS Number	2490298-72-9
PubChem ID	155694629
InChI Key	LXWDEVJSKWMYFZ-BGCUHRRXSA-N
Smiles	OC[C@H]1OC([C@@H]([C@H]([C@@H]1O)O)NC2=CC=C(N(=O)=O)C3=N[Se]N=C23)O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for SCOTfluor glucose probe 510

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	4.05	10

制备储备液 for SCOTfluor glucose probe 510

以下数据基于产品分子量 405.23。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.1 mM	24.68 mL	123.39 mL	246.77 mL
0.5 mM	4.94 mL	24.68 mL	49.35 mL
1 mM	2.47 mL	12.34 mL	24.68 mL
5 mM	0.49 mL	2.47 mL	4.94 mL

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产品说明书 for SCOTfluor glucose probe 510

分析证书/产品说明书

化学品安全技术说明书

参考文献 for SCOTfluor glucose probe 510

参考文献是支持产品生物活性的出版物。

Benson et al (2019) SCOTfluors: small, conjugatable, orthogonal, and tunable fluorophores for in vivo imaging of cell metabolism. Angew.Chem.Int.Ed.Engl. 58 6911 PMID: 30924239

Benson et al (2021) Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo. Nat.Commun. 12 2369 PMID: 33888691

If you know of a relevant reference for SCOTfluor glucose probe 510, please let us know.

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