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SCOTfluor lactic acid probe 510

Cat. No. 7448 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Fluorescent lactic acid probe
化学名： (2S)-2-Hydroxy-3-[(7-nitro-2,1,3-benzoselenadiazol-4-yl)amino]propanoic acid
纯度： ≥95% (HPLC)
说明书
引用文献
评论 (1)
文献 (1)
生物活性 Scientific Data 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for SCOTfluor lactic acid probe 510

SCOTfluor lactic acid probe 510 is a red fluorescent probe for imaging lactic acid metabolism in vivo. Excitation and emission maxima (λ) are 485 and 605 nm, respectively. Suitable for use with flow cytometry and super-resolution microscopy.

Scientific Data

Fluorescence Imaging Application of SCOTfluor lactic acid probe 510 in HeLa cells View Larger

Application of SCOTfluor lactic acid probe 510 in HeLa cells. TIRF microscopy image (left) of HeLa cells after incubation with SCOTfluor 510 lactate (100 μM). Multi-tracking of fluorescent particles corresponding to SCOTfluor 510 lactate labelling (right). Scale: 5 μm. Image kindly provided by Prof. Marc Vendrell, acquired by Dr Mathew Horrocks, School of Chemistry, University of Edinburgh.

许可信息

Sold under license from the University of Edinburgh

Optical Data for SCOTfluor lactic acid probe 510

SCOTfluor lactic acid probe 510 Dye Spectra
Emission Color Orange
λabs 485 nm
λem 605 nm
Closest Laser line 488 nm
Cell Permeable Yes
Application Fluorescence Microscopy, Super Resolution Microscopy (SRM), Flow Cytometry, in vivo

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技术数据 for SCOTfluor lactic acid probe 510

分子量 331.15
公式 C9H8N4O5Se
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 2351933-31-6
PubChem ID 146168509
InChI Key HQRYGRFCRSBEJR-LURJTMIESA-N
Smiles O[C@H](C(O)=O)CNC1=CC=C(N(=O)=O)C2=N[Se]N=C12

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for SCOTfluor lactic acid probe 510

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 3.31 10

制备储备液 for SCOTfluor lactic acid probe 510

以下数据基于产品分子量 331.15。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.1 mM 30.2 mL 150.99 mL 301.98 mL
0.5 mM 6.04 mL 30.2 mL 60.4 mL
1 mM 3.02 mL 15.1 mL 30.2 mL
5 mM 0.6 mL 3.02 mL 6.04 mL

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产品说明书 for SCOTfluor lactic acid probe 510

分析证书/产品说明书
化学品安全技术说明书

参考文献 for SCOTfluor lactic acid probe 510

参考文献是支持产品生物活性的出版物。

Benson et al (2019) SCOTfluors: Small, conjugatable, orthogonal, and tunable fluorophores for in vivo imaging of cell metabolism. Angew.Chem Int.Ed.Engl. 58 6911 PMID: 30924239

Monsorno et al (2023) Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice. Nat.Commun. 14 5749 PMID: 37717033

If you know of a relevant reference for SCOTfluor lactic acid probe 510, please let us know.

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关键词: SCOTfluor lactic acid probe 510, SCOTfluor lactic acid probe 510 supplier, metabolism, imaging, lactic, acid, fluorophore, fluorescent, in, vivo, Other, Fluorescent, Probes, 7448, Tocris Bioscience

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Good signal SCOTfluor lactic acid probe.
By Anonymous on 03/07/2024
分析类型： In Vitro
种属： Human
细胞系/组织： 293T

Primary cultured cells were pre-treated for 2 h with either control or with low glucose-containing medium. The SCOTfluor lactate was diluted in control or low glucose-medium to a concentration of 0.1 mM and applied onto cells for 1 h. Imaging was performed using a stage incubator and flow-cyto. Treament showed that lactate upregulated

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Fluorescent Dyes and Probes Research Product Guide

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