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说明： Inhibits NME2 nuclear translocation; primes ESCs for differentiation
化学名： [9S-(9α,10β,11β,13α)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1,3-dioxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl)-N-methylbenzamide
纯度： ≥98% (HPLC)
生物活性 for Stauprimide
Stauprimide is a small molecule that primes embryonic stem cells (ESCs) for differentiation. Interacts with NME2 and inhibits its nuclear translocation. Increases the efficiency of directed differentiation of mouse and human ESCs in vitro.
技术数据 for Stauprimide
| 分子量 | 584.62 |
| 公式 | C35H28N4O5 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 154589-96-5 |
| PubChem ID | 46245328 |
| InChI Key | MQCCJEYZKWZQHU-MPRCCEKMSA-N |
| Smiles | O=C(NC6=O)C1=C6C4=C3C2=C1C8=C(C=CC=C8)N2[C@](C[C@@H](N(C(C9=CC=CC=C9)=O)C)[C@H]7OC)([H])O[C@]7(C)N3C5=CC=CC=C45 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Stauprimide
参考文献 for Stauprimide
参考文献是支持产品生物活性的出版物。
Zhu et al (2009) A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell. 4 416 PMID: 19427291
关键词: Stauprimide, Stauprimide supplier, embryonic, stem, cells, ESCs, differentiation, inhibitors, inhibits, NME2, nuclear, translocation, transcription, factors, primes, Other, Transcription, Factors, and, iPSC, 3741, Tocris Bioscience
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