Sulfidefluor 7 AM

Cat. No. 4943 4 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： H₂S fluorescent probe

化学名： N-[2-[(Acetyloxy)methoxy]-2-oxoethyl]-N-[(3',6'-diazido-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)carbonyl]glycine (acetyloxy)methyl ester

引用文献 (4)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Sulfidefluor 7 AM

Sulfidefluor 7 AM is a reported to be a hydrogen sulphide (H₂S) fluorescent probe. Contains an acetoxymethyl ester, which enhances cell permeability and is hydrolyzed inside the cell to trap the probe. Used to visualize VEGF-induced H₂S production in human umbilical vein endothelial cells (HUVECS). Excitation wavelength ~ 495 nm; emission maximum ~ 520 nm.

许可信息

Sold under license from the Regents of the University of California

Optical Data for Sulfidefluor 7 AM

Emission Color	Green
λ_abs	495 nm
λ_em	520 nm
Cell Permeable	Yes
Application	Fluorescence Microscopy

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Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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技术数据 for Sulfidefluor 7 AM

分子量	685.55
公式	C₃₁H₂₃N₇O₁₂
储存	Store at -20°C
CAS Number	1416872-50-8
PubChem ID	89306941
InChI Key	QIAZHSBWGCYJGQ-UHFFFAOYSA-N
Smiles	O=C(O1)C2=C(C=CC(C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=O)=C2)C31C4=CC=C(N=[N+]=[N-])C=C4OC5=C3C=CC(N=[N+]=[N-])=C5

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Sulfidefluor 7 AM

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	13.71	20

制备储备液 for Sulfidefluor 7 AM

以下数据基于产品分子量 685.55。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.2 mM	7.29 mL	36.47 mL	72.93 mL
1 mM	1.46 mL	7.29 mL	14.59 mL
2 mM	0.73 mL	3.65 mL	7.29 mL
10 mM	0.15 mL	0.73 mL	1.46 mL

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产品说明书 for Sulfidefluor 7 AM

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Sulfidefluor 7 AM

参考文献是支持产品生物活性的出版物。

Lin et al (2013) Cell-trappable fluorescent probes for endogenous hydrogen sulfide signaling and imaging H₂O₂-dependent H₂S production. Proc.Natl.Acad.Sci.USA. 110 7131 PMID: 23589874

Lippert et al (2011) Reaction-based fluorescent probes for selective imaging of hydrogen sulfide in living cells. J.Am.Chem.Soc. 133 10078 PMID: 21671682

If you know of a relevant reference for Sulfidefluor 7 AM, please let us know.

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关键词: Sulfidefluor 7 AM, Sulfidefluor 7 AM supplier, hydrogen, sulphide, H2S, fluorescent, probe, Fluorescent, Cell, Indicators, and, Sensors, 4943, Tocris Bioscience

4 篇 Sulfidefluor 7 AM 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Sulfidefluor 7 AM 的部分引用包括：

Margreet R et al (2020) Periprocedural Hydrogen Sulfide Therapy Improves Vascular Remodeling and Attenuates Vein Graft Disease. J Am Heart Assoc 9 e016391 PMID: 33146045

Cheng et al (2016) Restoration of Hydrogen Sulfide Production in Diabetic Mice Improves Reparative Function of Bone Marrow Cells. Circulation 134 1467 PMID: 27660293

Chhabra et al (2018) Glucose-6-phosphate dehydrogenase is critical for suppression of cardiac hypertrophy by H2S. Cell Death Discov 4 6 PMID: 29531803

Xiaofeng et al (2021) Intracellular H2S production is an autophagy-dependent adaptive response to DNA damage. Cell Chem Biol 28 1669-1678.e5 PMID: 34166610

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