SUN-B 8155

Pricing Availability   Qty
说明: Non-peptide calcitonin agonist
化学名: 5-[1-[(2-Aminophenyl)imino]ethyl]-1,6-dihydroxy-4-methyl-2(1H)-pyridone
说明书
引用文献
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生物活性 for SUN-B 8155

SUN-B 8155 is a non-peptide calcitonin (CT) receptor agonist that fully stimulates cAMP production in CHO/hCTR cells (EC50 = 21 μM). Causes a significant reduction in serum calcium concentrations in vivo following i.p. administration.

化合物库 for SUN-B 8155

SUN-B 8155 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for SUN-B 8155

分子量 273.29
公式 C14H15N3O3
储存 Store at +4°C
CAS Number 345893-91-6
PubChem ID 16079007
InChI Key IMUCOECFKIWBSW-LCYFTJDESA-N
Smiles O=C1C=C(C)C(/C(C)=N/C2=C(N)C=CC=C2)=C(O)N1O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for SUN-B 8155

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 27.32 100

制备储备液 for SUN-B 8155

以下数据基于产品分子量 273.29。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.66 mL 18.3 mL 36.59 mL
5 mM 0.73 mL 3.66 mL 7.32 mL
10 mM 0.37 mL 1.83 mL 3.66 mL
50 mM 0.07 mL 0.37 mL 0.73 mL

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产品说明书 for SUN-B 8155

分析证书/产品说明书
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参考文献 for SUN-B 8155

参考文献是支持产品生物活性的出版物。

Katayama et al (2001) Discovery of a non-peptide small molecule that selectively mimics the biological actions of calcitonin. Biochim.Biophys.Acta 1526 183 PMID: 11325540


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查看全部 Calcitonin and Related Receptor Agonists

关键词: SUN-B 8155, SUN-B 8155 supplier, Non-peptide, calcitonin, CT, receptors, agonists, SUNB8155, Calcitonin, and, Related, Receptors, 2550, Tocris Bioscience

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该领域的文献

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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.