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Submit ReviewSUN-B 8155 is a non-peptide calcitonin (CT) receptor agonist that fully stimulates cAMP production in CHO/hCTR cells (EC50 = 21 μM). Causes a significant reduction in serum calcium concentrations in vivo following i.p. administration.
SUN-B 8155 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。
分子量 | 273.29 |
公式 | C14H15N3O3 |
储存 | Store at +4°C |
CAS Number | 345893-91-6 |
PubChem ID | 16079007 |
InChI Key | IMUCOECFKIWBSW-LCYFTJDESA-N |
Smiles | O=C1C=C(C)C(/C(C)=N/C2=C(N)C=CC=C2)=C(O)N1O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
DMSO | 27.32 | 100 |
以下数据基于产品分子量 273.29。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 3.66 mL | 18.3 mL | 36.59 mL |
5 mM | 0.73 mL | 3.66 mL | 7.32 mL |
10 mM | 0.37 mL | 1.83 mL | 3.66 mL |
50 mM | 0.07 mL | 0.37 mL | 0.73 mL |
参考文献是支持产品生物活性的出版物。
Katayama et al (2001) Discovery of a non-peptide small molecule that selectively mimics the biological actions of calcitonin. Biochim.Biophys.Acta 1526 183 PMID: 11325540
If you know of a relevant reference for SUN-B 8155, please let us know.
关键词: SUN-B 8155, SUN-B 8155 supplier, Non-peptide, calcitonin, CT, receptors, agonists, SUNB8155, Calcitonin, and, Related, Receptors, 2550, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.