Taxol Janelia Fluor® 526

Pricing Availability   Qty
说明: Green-fluorescent taxol derivative; binds microtubules. Used for: microtubules imaging. Application: confocal microscopy, super resolution microscopy. Suitable for live cell imaging
别名: Janelia Fluor 526-TXL
化学名: 4-((8-(((1S,2R)-3-(((2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-12-(benzoyloxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl)oxy)-2-hydroxy-3-oxo-1-phenylpropyl)amino)-8-oxooctyl)carbamoyl)-2-(3-(3,3-difluoroazetidin-1-ium-1-ylidene)-6-(3,3-difluoroazetidin-1-yl)-2,7-difluoro-3H-xanthen-9-yl)benzoate trifluoroacetate
纯度: ≥85% (HPLC)
说明书
引用文献
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生物活性 for Taxol Janelia Fluor® 526

Key information: Taxol Janelia Fluor® 526 is a fluorogenic, green-fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton. Suitable for live cell imaging.

Used for: direct imaging of the microtubule cytoskeleton.

Application: confocal microscopy, Super Resolution Microscopy (SRM) including STED.

Properties and Photophysical Data: Taxol Janelia Fluor® 526 is fluorogenic: it fluoresces only once bound to microtubules, enabling hassle-free no-wash experiments. Excitation and emission maxima (λ) are 531 nm and 549 nm, respectively; quantum yield = 0.87; extinction coefficient = 118,000 M-1cm-1.

许可信息

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Optical Data for Taxol Janelia Fluor® 526

Taxol Janelia Fluor<sup>®</sup> 526 Dye Spectra
Emission Color Yellow
λabs 531 nm
λem 549 nm
Extinction Coefficient (ε) 118000 M-1cm-1
Quantum Yield (φ) 0.87
Application Confocal Microscopy, Super Resolution Microscopy (SRM), STED

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技术数据 for Taxol Janelia Fluor® 526

分子量 1507.42
公式 C73H74F6N4O17.CF3CO2H
储存 Store at -20°C
纯度 ≥85% (HPLC)
CAS Number 2410613-93-1
InChI Key WYTXGBVNWCQFKK-SOCHEKDQSA-N
Smiles [H][C@@]12C[C@@H]([C@]3(C([C@@H](C4=C([C@@H](OC([C@@H]([C@H](C5=CC=CC=C5)NC(CCCCCCCNC(C6=CC(C7=C8C=C(/C(C=C8OC9=C7C=C(C(N%10CC(F)(C%10)F)=C9)F)=[N+]%11CC(F)(C/%11)F)F)=C(C([O-])=O)C=C6)=O)=O)O)=O)C[C@@]([C@H]([C@@]3([C@]1(OC(C)=O)CO2)[H])OC(C%12=CC=CC=C%12)=O)(C4(C)C)O)C)O)=O)C)O.O=C(O[H])C(F)(F)F

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Taxol Janelia Fluor® 526

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 15.07 10

制备储备液 for Taxol Janelia Fluor® 526

以下数据基于产品分子量 1507.42。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.1 mM 6.63 mL 33.17 mL 66.34 mL
0.5 mM 1.33 mL 6.63 mL 13.27 mL
1 mM 0.66 mL 3.32 mL 6.63 mL
5 mM 0.13 mL 0.66 mL 1.33 mL

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产品说明书 for Taxol Janelia Fluor® 526

参考文献 for Taxol Janelia Fluor® 526

参考文献是支持产品生物活性的出版物。

Zheng et al (2019) Rational design of fluorogenic and spontaneously blinking labels for super-resolution imaging. ACS Cent.Sci. 5 1602 PMID: 31572787


If you know of a relevant reference for Taxol Janelia Fluor® 526, please let us know.

关键词: Taxol Janelia Fluor 526, Taxol Janelia Fluor 526 supplier, Fluorogenic, green, fluorescent, taxol, microtubule, cytoskeleton, stains, probes, dyes, Janelia, Fluor, 526-TXL, Microtubule, Probes, 7315, Tocris Bioscience

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