Taxol Janelia Fluor^® 646

Cat. No. 6266 2 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Red-fluorescent taxol derivative. Used for: microtubule staining. Application: confocal microscopy, fluorescence microscopy; protocol available

化学名： 2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-4-(((2S)-1-(((2aR,4S,4aS,6R,9S,11S,12S,12bS)-6,12b-diacetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-4-yl)oxy)-1-oxopropan-2-yl)carbamoyl)benzoate

纯度： ≥95% (HPLC)

引用文献 (2)

实验方案 (1)

文献 (1)

生物活性 Scientific Data 技术数据溶解性计算器说明书参考文献

生物活性 for Taxol Janelia Fluor^® 646

Key information: Taxol Janelia Fluor^® 646 is a red-fluorescent taxol derivative for direct imaging of the microtubule cytoskeleton.

Used for: microtubule cytoskeleton imaging.

Application: confocal microscopy, fluorescence microscopy.

Properties and Photophysical Data: Excitation and emission maxima (λ) are 655 nm and 671 nm, respectively.

For more information on how Taxol-Janelia Fluor^® 646 may be used, see our protocol.

Scientific Data

Confocal Microscopy

COS7 cells dye-labeled with Taxol Janelia Fluor 646

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Application of Taxol Janelia Fluor^® 646, dye on COS7 cells. COS7 cells were labeled with 3 µM Taxol Janelia Fluor^® 646 for one hour at 37°C. Images were taken on a Leica TCS SP8 Confocal Laser Scanning Microscope. All images kindly provided by Prof. Christian Soeller, University of Exeter; acquired by Evelina Lucinskaite, Anna Meletiou and Alexander Clowsley.

许可信息

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus

Optical Data for Taxol Janelia Fluor^® 646

Taxol Janelia Fluor<sup>®</sup> 646 Dye Spectra

Emission Color	Red
λ_abs	655 nm
λ_em	671 nm
Application	Fluorescence Microscopy, Confocal Microscopy

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技术数据 for Taxol Janelia Fluor^® 646

分子量	1403.62
公式	C₇₉H₈₂N₄O₁₈Si
储存	Store at -20°C
纯度	≥95% (HPLC)
Smiles	O=C(C)O[C@]12C([C@@]3(C)[C@@H](OC([C@H](C)NC(C4=CC=C(C([O-])=O)C(C5=C(C=C/6)C([Si](C)(C)C7=C5C=CC(N8CCC8)=C7)=CC6=[N+]9CCC\9)=C4)=O)=O)C[C@H]1OC2)[C@H](OC(C%10=CC=CC=C%10)=O)[C@@]%11(O)C(C)(C)C([C@@H](OC(C)=O)C3=O)=C(C)[C@@H](OC([C@H](O)[C@H](C%12=CC=CC=C%12)NC(C%13=CC=CC=C%13)=O)=O)C%11

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Taxol Janelia Fluor^® 646

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	28.07	20

制备储备液 for Taxol Janelia Fluor^® 646

以下数据基于产品分子量 1403.62。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.2 mM	3.56 mL	17.81 mL	35.62 mL
1 mM	0.71 mL	3.56 mL	7.12 mL
2 mM	0.36 mL	1.78 mL	3.56 mL
10 mM	0.07 mL	0.36 mL	0.71 mL

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产品说明书 for Taxol Janelia Fluor^® 646

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Taxol Janelia Fluor^® 646

参考文献是支持产品生物活性的出版物。

If you know of a relevant reference for Taxol Janelia Fluor^® 646, please let us know.

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关键词: Taxol Janelia Fluor 646, Taxol Janelia Fluor 646 supplier, red, fluorescent, taxol, derivative, cytoskeletal, probes, microtubules, fluorogenic, Organelle, and, Cell, Structure, Stains, Microtubule, Probes, 6266, Tocris Bioscience

2 篇 Taxol Janelia Fluor^® 646 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Taxol Janelia Fluor^® 646 的部分引用包括：

Cai et al (2023) Optical blood-brain-tumor barrier modulation expands therapeutic options for glioblastoma treatment. Nat.Commun. 14 4934 PMID: 37582846

Lemaître et al (2021) Capturing T lymphocytes' dynamic interactions with human neural cells using time-lapse microscopy. Front.Immunol. 12 PMID: 33968073

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