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TC 1698 dihydrochloride

Cat. No. 2518 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

2518 has been discontinued.

说明： α7-selective agonist
化学名： 2-(3-Pyridinyl)-1-azabicyclo[3.2.2]nonane dihydrochloride
纯度： ≥98% (HPLC)
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生物活性 技术数据 说明书 参考文献

生物活性 for TC 1698 dihydrochloride

TC 1698 dihydrochloride is a selective nicotinic α7 receptor agonist (EC50 = 440 nM). Also displays weak partial agonist/antagonist activity at β-subunit-containing receptors. Neuroprotective.

技术数据 for TC 1698 dihydrochloride

分子量 275.22
公式 C13H18N2.2HCl
储存 Desiccate at RT
纯度 ≥98% (HPLC)
CAS Number 787587-06-8
PubChem ID 21094258
InChI Key ZQUQBCHNSBJMCG-UHFFFAOYSA-N
Smiles C1(C2N3CCC(CC3)CC2)=CC=CN=C1.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for TC 1698 dihydrochloride

分析证书/产品说明书
化学品安全技术说明书

参考文献 for TC 1698 dihydrochloride

参考文献是支持产品生物活性的出版物。

Marrero et al (2004) The neuroprotective effect of 2-(3-Pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a novel α7 ligand, is prevented through angiotensin II activation of a tyrosine phosphatase. J.Pharmacol.Exp.Ther. 309 16 PMID: 14722323

Papke et al (2005) Rhesus monkey α7 nicotinic acetylcholine receptors: comparisons to human α7 receptors expressed in Xenopus oocytes. Eur.J.Pharmacol. 524 11 PMID: 16266703

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关键词: TC 1698 dihydrochloride, TC 1698 dihydrochloride supplier, α7, alpha7-selective, agonists, α7Nicotinic, a7Nicotinic, Receptors, Acetylcholine, nAChR, TC1698, dihydrochloride, Nicotinic, (a7), 2518, Tocris Bioscience

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