tri-GalNAc-C5-AF647

Pricing Availability   Qty
说明: Fluorescent ASGPR ligand. Application: flow cytometry, fluorescence microscopy
纯度: ≥90%
说明书
引用文献
评论

生物活性 for tri-GalNAc-C5-AF647

Key information: tri-GalNAc-C5-AF647 is a fluorescent asialoglycoprotein receptor (ASGPR) ligand. Suitable for live-cell imaging. Can be used for lysosomal uptake imaging in live cells. Also can be used for isolating hepatocytes due to its uptake via ASGPR receptor.

Application: Flow cytometry, fluorescence microscopy.

Properties and Photophysical Data: Suitable for multiplexing and can be combined with DAPI (Cat. No. 5748) counter-staining. Excitation and emission maxima (λ) are 663 and 684 nm, respectively.

Optical Data for tri-GalNAc-C5-AF647

tri-GalNAc-C5-AF647 Dye Spectra
λabs 663 nm
λem 684 nm
Cell Permeable Yes
Application Flow Cytometry, Fluorescence Microscopy

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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技术数据 for tri-GalNAc-C5-AF647

分子量 2456.74
公式 C103H162N16O44S4
储存 Store at -20°C
纯度 ≥90%
InChI Key YADZNIHLQXJZAN-PPECRGGSSA-N
Smiles O=C(NC(COCC1=CN(N=N1)CCOCCOCCOCCO[C@H]2O[C@H]([C@@H](O)[C@@H](O)[C@@H]2NC(C)=O)CO)(COCC3=CN(N=N3)CCOCCOCCOCCO[C@@H]4O[C@@H]([C@H](O)[C@H](O)[C@H]4NC(C)=O)CO)COCC5=CN(N=N5)CCOCCOCCOCCO[C@H]6O[C@H]([C@@H](O)[C@@H](O)[C@@H]6NC(C)=O)CO)CCCCCNC(CCCCCC7(C(/C=C/C=C/C=C8C(C)(C9=C(N\8CCCS(=O)(O)=O)C=CC(S(=O)(O)=O)=C9)C)=[N+](C%10=C7C=C(C=C%10)S(=O)(O)=O)CCCS(=O)([O-])=O)C)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for tri-GalNAc-C5-AF647

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 24.57 10

制备储备液 for tri-GalNAc-C5-AF647

以下数据基于产品分子量 2456.74。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.1 mM 4.07 mL 20.35 mL 40.7 mL
0.5 mM 0.81 mL 4.07 mL 8.14 mL
1 mM 0.41 mL 2.04 mL 4.07 mL
5 mM 0.08 mL 0.41 mL 0.81 mL

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产品说明书 for tri-GalNAc-C5-AF647

参考文献 for tri-GalNAc-C5-AF647

参考文献是支持产品生物活性的出版物。

Sanhueza et al (2017) Efficient liver targeting by polyvalent display of a compact ligand for the asialoglycoprotein receptor. J.Am.Chem.Soc. 139 3528 PMID: 28230359


If you know of a relevant reference for tri-GalNAc-C5-AF647, please let us know.

关键词: tri-GalNAc-C5-AF647, tri-GalNAc-C5-AF647 supplier, triGalNAcC5AF647, ASGPR, asialoglycoprotein, receptor, ligand, hepatocytes, conjugation, LYTAC, lysosomal, targeting, chimera, alkylc5, degradation, degraders, Building, Blocks, in, vivo, Fluorescent, Lysosome, Probes, Receptor, 7901, Tocris Bioscience

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