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Submit ReviewU-54494A hydrochloride
Discontinued Product
0498 has been discontinued.
说明： κ agonist
化学名： cis-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzamide hydrochloride
生物活性 for U-54494A hydrochloride
κ-opioid agonist and anticonvulsant. Perhaps acts as an NMDA antagonist.
技术数据 for U-54494A hydrochloride
| 分子量 | 391.77 |
| 公式 | C18H24Cl2N2O.HCl |
| 储存 | Store at RT |
| CAS Number | 112465-94-8 |
| PubChem ID | 183470 |
| InChI Key | JUBNVWGVNWIXMB-SJORKVTESA-N |
| Smiles | O=C(C3=CC(Cl)=C(Cl)C=C3)N([C@H]1[C@@H](N2CCCC2)CCCC1)C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for U-54494A hydrochloride
分析证书目前不在网上提供。
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参考文献 for U-54494A hydrochloride
参考文献是支持产品生物活性的出版物。
Proietti et al (1991) In vitro depressant effects of U-54494A, an anticonvulsant related to kappa opioids in the hippocampus. Neuropharmacology 30 637 PMID: 1656303
Sethy and Sage (1992) Modulation of release of acetylcholine from the striatum by a proposed excitatory amino acid antagonist U-54494A: comparison with known antagonists, D.pam and phen. Neuropharmacology 31 111 PMID: 1348110
Voigtlander et al (1987) U-54494A: a unique anticonvulsant related to kappa opioid agonists. J.Pharmacol.Exp.Ther. 243 542 PMID: 2824750
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关键词: U-54494A hydrochloride, U-54494A hydrochloride supplier, agonists, κ-opioid, kappa-opioid, KOP, Receptors, OP2, Kappa, Opioid, 0498, Tocris Bioscience
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