VIP (human, rat, mouse, rabbit, canine, porcine)

Pricing Availability   Qty
说明: Involved in neurotransmission and smooth muscle relaxation
别名: Vasoactive Intestinal Peptide (human,rat,mouse,rabbit,canine,porcine)
纯度: ≥95% (HPLC)
说明书
引用文献 (3)
评论 (1)

生物活性

VIP (human, rat, mouse, rabbit, canine, porcine) is a neuropeptide with many biological actions; plays a role in neurotransmission, smooth muscle relaxation and has trophic and mitogenic actions.

技术数据

分子量 3325.83
公式 C147H238N44O42S
序列 HSDAVFTDNYTRLRKQMAVKKYLNSILN

(Modifications: Asn-28 = C-terminal amide)

储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 40077-57-4
PubChem ID 16140438
InChI Key HEOYHMUESMJFDC-RIWXPGAOSA-N
Smiles [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(N)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据

溶解性 Soluble to 1 mg/ml in water

产品说明书

分析证书/产品说明书
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参考文献

参考文献是支持产品生物活性的出版物。

Harmar et al (1998) International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide. Pharmacol.Rev. 50 265 PMID: 9647867

Laburthe and Couvineau (2002) Molecular pharmacology and structure of VPAC receptors for VIP and PACAP. Regul.Pept. 108 165 PMID: 12220741


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关键词: VIP (human, rat, mouse, rabbit, canine, porcine), VIP (human, rat, mouse, rabbit, canine, porcine) supplier, Involved, neurotransmission, smooth, muscle, relaxation, Vasoactive, Intestinal, Peptide, Receptors, VPAC, VIP, agonists, (human,, rat,, mouse,, rabbit,, canine,, porcine), 1911, Tocris Bioscience

3 篇 VIP (human, rat, mouse, rabbit, canine, porcine) 的引用文献

引用文献是使用了 Tocris 产品的出版物。 VIP (human, rat, mouse, rabbit, canine, porcine) 的部分引用包括:

Alcolado et al (2014) Cystic fibrosis transmembrane conductance regulator dysfunction in VIP knockout mice. Am J Physiol Cell Physiol 307 C195 PMID: 24898584

Piet et al (2016) Vasoactive Intestinal Peptide Excites GnRH Neurons in Male and Female Mice. Endocrinology. 157 3621 PMID: 27501185

Gey et al (2016) Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury. Open Biol 6 PMID: 27581653


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VIP (human, rat, mouse, rabbit, canine, porcine) 的评论

平均评分: 5 (Based on 1 Review.)

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test.
By Jacob Painter on 07/07/2022
分析类型: In Vitro
种属: Mouse
细胞系/组织: Lymphoid Cells

Used in vitro. Was able to stimulate at 1 uM. Was easy to reconstitute.