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Submit ReviewVIP (human, rat, mouse, rabbit, canine, porcine) is a neuropeptide with many biological actions; plays a role in neurotransmission, smooth muscle relaxation and has trophic and mitogenic actions.
分子量 | 3325.83 |
公式 | C147H238N44O42S |
序列 |
HSDAVFTDNYTRLRKQMAVKKYLNSILN (Modifications: Asn-28 = C-terminal amide) |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 40077-57-4 |
PubChem ID | 16140438 |
InChI Key | HEOYHMUESMJFDC-RIWXPGAOSA-N |
Smiles | [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性 | Soluble to 1 mg/ml in water |
参考文献是支持产品生物活性的出版物。
Harmar et al (1998) International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide. Pharmacol.Rev. 50 265 PMID: 9647867
Laburthe and Couvineau (2002) Molecular pharmacology and structure of VPAC receptors for VIP and PACAP. Regul.Pept. 108 165 PMID: 12220741
If you know of a relevant reference for VIP (human, rat, mouse, rabbit, canine, porcine), please let us know.
关键词: VIP (human, rat, mouse, rabbit, canine, porcine), VIP (human, rat, mouse, rabbit, canine, porcine) supplier, Involved, neurotransmission, smooth, muscle, relaxation, Vasoactive, Intestinal, Peptide, Receptors, VPAC, VIP, agonists, (human,, rat,, mouse,, rabbit,, canine,, porcine), 1911, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 VIP (human, rat, mouse, rabbit, canine, porcine) 的部分引用包括:
Alcolado et al (2014) Cystic fibrosis transmembrane conductance regulator dysfunction in VIP knockout mice. Am J Physiol Cell Physiol 307 C195 PMID: 24898584
Piet et al (2016) Vasoactive Intestinal Peptide Excites GnRH Neurons in Male and Female Mice. Endocrinology. 157 3621 PMID: 27501185
Gey et al (2016) Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury. Open Biol 6 PMID: 27581653
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平均评分: 5 (Based on 1 Review.)
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Used in vitro. Was able to stimulate at 1 uM. Was easy to reconstitute.