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YE 120

Cat. No. 4457 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： GPR35 agonist
化学名： 2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]propanedinitrile
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for YE 120

YE 120 is a GPR35 agonist (EC50 = 32 nM in DMR assays). Also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM).

化合物库 for YE 120

YE 120 is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。

技术数据 for YE 120

分子量 330.17
公式 C16H9Cl2N3O
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 383124-82-1
PubChem ID 12138435
InChI Key RSWZFAPYKOARNG-UHFFFAOYSA-N
Smiles CC(C(C2=CC=C(Cl)C(Cl)=C2)(C)O1)=C(C#N)/C1=C(C#N)\C#N

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for YE 120

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 33.02 100

制备储备液 for YE 120

以下数据基于产品分子量 330.17。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.03 mL 15.14 mL 30.29 mL
5 mM 0.61 mL 3.03 mL 6.06 mL
10 mM 0.3 mL 1.51 mL 3.03 mL
50 mM 0.06 mL 0.3 mL 0.61 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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参考文献 for YE 120

参考文献是支持产品生物活性的出版物。

Deng et al (2011) Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists. J.Med.Chem. 54 7385 PMID: 21950657

If you know of a relevant reference for YE 120, please let us know.

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关键词: YE 120, YE 120 supplier, YE120, gpr35, agonists, orphan, receptors, GPR35, 4457, Tocris Bioscience

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