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Submit ReviewCID 5951923
Description: Krüppel-like factor 5 (KLF5) inhibitor
Chemical Name: 2-[Methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl (E)-3-(3-nitrophenyl)prop-2-enoate
Purity: ≥97% (HPLC)
Biological Activity for CID 5951923
CID 5951923 is an inhibitor of Krüppel-like factor 5 (KLF5) transcription factor (IC50 = 2.3 μM). Selectively active against colon cancer cells in a panel of 60 different cancer cell lines.
Technical Data for CID 5951923
| M. Wt | 382.39 |
| Formula | C16H18N2O7S |
| Storage | Store at +4°C |
| Purity | ≥97% (HPLC) |
| CAS Number | 749872-43-3 |
| PubChem ID | 5951923 |
| InChI Key | URVRJYLSUVXWBC-AATRIKPKSA-N |
| Smiles | O=C(OCC(N(C)C2CS(CC2)(=O)=O)=O)/C=C/C1=CC([N+]([O-])=O)=CC=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for CID 5951923
References for CID 5951923
References are publications that support the biological activity of the product.
Bialkowska et al (2011) Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening. Mol.Cancer Ther. 10 2043 PMID: 21885866
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Keywords: CID 5951923, CID 5951923 supplier, CID5951923, krueppel, kruppel, krüppel-like, factors, klf5, inhibitors, inhibits, Other, Transcription, Factors, 4446, Tocris Bioscience
Citations for CID 5951923
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