Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewBRD 7552
Description: PDX1 transcription factor inducer; increases insulin expression
Chemical Name: Methyl [2,3-O-bis(Benzo[1,3]dioxol-5-yl-carbamoyl)]-4-O-(4-ethoxycarbonyl-phenylcarbamoyl)-α-D-glucopyranoside
Purity: ≥98% (HPLC)
Biological Activity for BRD 7552
BRD 7552 is a PDX1 transcription factor inducer; up regulates PDX1 expression in both primary human islets and ductal cells. Induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. Increases insulin expression in PANC-1 cells, primary human islets and human duct-derived cells.
Technical Data for BRD 7552
| M. Wt | 711.63 |
| Formula | C33H33N3O15 |
| Storage | Store at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 1137359-47-7 |
| PubChem ID | 23891512 |
| InChI Key | AAOLIMLEFKWKOY-IXMSMLDRSA-N |
| Smiles | OC[C@@H]1[C@@H](OC(NC6=CC=C(C(OCC)=O)C=C6)=O)[C@H](OC(NC4=CC=C(OCO5)C5=C4)=O)[C@@H](OC(NC2=CC(OCO3)=C3C=C2)=O)[C@@H](OC)O1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for BRD 7552
References for BRD 7552
References are publications that support the biological activity of the product.
Yuan et al (2013) A small-molecule inducer of PDX1 expression identified by high-throughput screening. Chem.Biol. 20 1513 PMID: 24290880
View Related Products by Target
Keywords: BRD 7552, BRD 7552 supplier, BRD7552, pancreatic, and, duodenal, homeobox, 1, PDX1, transcription, factor, inducers, epigenetic, insulin, diabetes, Other, Transcription, Factors, 5230, Tocris Bioscience
Citations for BRD 7552
Citations are publications that use Tocris products.
Currently there are no citations for BRD 7552.
Reviews for BRD 7552
There are currently no reviews for this product. Be the first to review BRD 7552 and earn rewards!
Have you used BRD 7552?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image