5-HT1F Receptors

Serotonin 5-HT1F receptors, previously known as 5-HT1Eβ receptors, are located primarily in the hippocampus, cortex and dorsal raphe nucleus. The human 5-HT1F receptor is closely related to the 5-ht1E receptor and its gene has been localized to chromosome 3 (3q11).

Products
Background
Literature (1)
Gene Data

5-HT1F Receptor Agonists

Cat. No. Product Name / Activity
2451 LY 344864 hydrochloride
Potent and selective 5-HT1F agonist
4657 Zolmitriptan
Potent 5-HT1B/1D/1F agonist

Serotonin 5-HT1F receptors, previously known as 5-HT1Eβ receptors, are located primarily in the hippocampus, cortex and dorsal raphe nucleus. The human 5-HT1F receptor is closely related to the 5-ht1E receptor and its gene has been localized to chromosome 3 (3q11).The physiological role of 5-HT1F receptors is currently unknown.

External sources of pharmacological information for 5-HT1F Receptors :

Literature for 5-HT1F Receptors

Tocris offers the following scientific literature for 5-HT1F Receptors to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


5-HT Receptors Scientific Review

5-HT Receptors Scientific Review

Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.

5-HT1F Receptor Gene Data

Species Gene Symbol Gene Accession No. Protein Accession No.
Human HTR1F NM_000866 P30939
Mouse Htr1f NM_008310 Q02284
Rat Htr1f NM_021857 P30940