PPARδ
Peroxisome proliferator-activated receptor delta (PPARδ), also known as PPARβ, is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression.
PPARδ Agonists |
|
|---|---|
| Cat. No. | Product Name / Activity |
| 2229 | GW 0742 |
| Highly selective, potent PPARδ agonist | |
| 5674 | GW 501516 |
| Potent and selective PPARδ agonist | |
PPARδ Antagonists |
|
| Cat. No. | Product Name / Activity |
| 3433 | GSK 0660 |
| Selective PPARδ antagonist | |
| 3961 | GSK 3787 |
| Potent and selective PPARδ antagonist | |
Peroxisome proliferator-activated receptor delta (PPARδ), also known as PPARβ, is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor (RXR) to regulate gene expression.
PPARδ displays a ubiquitous expression pattern and is thought to regulate placental and gut development, fatty acid oxidation, adaptive thermogenesis, control of cell proliferation and differentiation and tissue repair. The human gene encoding PPARδ has been localized to chromosome 6 (6p21.2).