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Description: Myosin-ATPase inhibitor
Biological Activity for 2,3-Butanedione monoxime
Inhibits myosin-ATPase and induces Ca2+ release from the sarcoplasmic reticulum. Also an anticonvulsant, able to suppress current induced by GABA, glycine and kainate, possibly by altering the phosphorylation state of sites on their receptors.
Technical Data for 2,3-Butanedione monoxime
| M. Wt | 101.1 |
| Storage | Store at RT |
| CAS Number | 57-71-6 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for 2,3-Butanedione monoxime
Certificate of Analysis is currently unavailable on-line.
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References for 2,3-Butanedione monoxime
References are publications that support the biological activity of the product.
Phillips and Altschuld (1996) 2,3-Butanedione 2-monoxime (BDM) induces calcium release from canine cardiac sarcoplasmic reticulum. Biochem.Biophys.Res.Commun. 229 154 PMID: 8954098
Soeno et al (1999) BDM (2,3-butanedione monoxime), an inhibitor of myosin-actin interaction, suppresses myofibrillogenesis in skeletal muscle cells in culture. Cell Tissue Res. 295 307 PMID: 9931377
Wiggins et al (1980) Inotropic actions of diacetyl monoxime in cat ventricular muscle. J.Pharmacol.Exp.Ther. 212 217 PMID: 6243361
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Keywords: 2,3-Butanedione monoxime, 2,3-Butanedione monoxime supplier, Myosin, General, Calcium, Signaling, Agents, 0936, Tocris Bioscience
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